Test: GRE Subject Test: Biochemistry, Cell, and Molecular Biology

1.

During the first step of glycolysis, glucose is phosphorylated by hexokinase. What is the purpose of this reaction?

The phophorylation of glucose changes the structure of glucose so that it can be isomerized in the next step

The phophorylation of glucose creates a negative charge on the glucose molecule so that it cannot pass through the plasma membrane

The proton released via the phosphorylation reaction is necessary for the formation of NADH

The hydrolysis of ATP is necessary to start the glycolytic pathway

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