Test: Biochemistry

There are at least four types of glucose transporter in the body. GLUT1 and GLUT3 are located in most tissues including the brain and the red blood cells. These glucose transporters rapidly take up glucose from the blood but have the lowest  value. GLUT2 is commonly found in the liver and the pancreas. GLUT2 has a lower affinity for glucose but has the highest  value. GLUT4 is common in skeletal tissues and in adipose tissues. This transporter is normally not active for uptake unless stimulated by insulin or during exercise.  

1.

In patients with diabetes mellitus type II, one of the best form of treatment is exercise. Which of the following statements is/are supportive for exercise as a potential treatment for type II diabetes? 

I. Exercise activates the GLUT4 transporter

II. Exercise activates the GLUT1 receptor

III. Exercise allows the skeletal muscles to uptake glucose from circulation without the need for insulin

I, II, and III

I only

III only

II only

I and III

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