NCLEX : Neural Pharmacology

Study concepts, example questions & explanations for NCLEX

varsity tutors app store varsity tutors android store

Example Questions

← Previous 1

Example Question #16 : Drug Identification

A client has been taking daily doses of Paroxetine for 6 months and has asked for an information with the nurse about going off the medication. What should the nurse emphasize in the information session?

Possible Answers:

Taper the medication to avoid discontinuation syndrome

Stop taking the medication immediately, increase physical activity level for 2-3 weeks to counteract side effects

Urge the client to continue taking the medication until he consults a psychotherapist

Advise the patient of probable weight gain after going off the medication

Correct answer:

Taper the medication to avoid discontinuation syndrome

Explanation:

Clients taking Paroxetine may experience withdrawal and continuation syndrome. To minimize symptoms, taper the medication over a period of 3 or more weeks.

Example Question #17 : Drug Identification

What type of antidepressant is fluoxetine?

Possible Answers:

Selective serotonin re-uptake inhibitor (SSRI)

Tetracyclic antidepressant

Monoamine oxidase inhibitors (MAOI) 

Norepinephrine reuptake inhibitor (NRI)

Correct answer:

Selective serotonin re-uptake inhibitor (SSRI)

Explanation:

Fluoxetine is an example of a selective serotonin re-uptake inhibitor (SSRI). SSRI's limit the amount of serotonin that the presynaptic cell that secreted it, cat re-uptake. This increases the time and amount that serotonin is in the synaptic cleft, and bound to postsynaptic receptors, leading to anti-depressant properties. The other drugs are all antidepressants, but are sold under other names.

Example Question #1 : Neural Pharmacology

What drug class is clomipramine?

Possible Answers:

Tricyclic antidepressant

Monoamine oxidase inhibitor (MAOI)

Selective serotonin reuptake inhibitor (SSRI)

Serotonin modulator and stimulator (SMS)

Correct answer:

Tricyclic antidepressant

Explanation:

Clomipramine is a tricyclic antidepressant. Drugs in this class function primarily by blocking serotonin and norepinephrine transporters, resulting in an increase in the levels of these neurotransmitters in the synapse, and thus an increase in their effects due to staying bound to postsynaptic receptors for longer. 

Example Question #2 : Neural Pharmacology

What class of drug is trazodone?

Possible Answers:

Tricyclic antidepressant

Tetracyclic antidepressant

Serotonin antagonist and reuptake inhibitor (SARI)

Norepinephrine reuptake inhibitor (NRI)

Correct answer:

Serotonin antagonist and reuptake inhibitor (SARI)

Explanation:

Trazodone is a serotonin antagonist and reuptake inhibitor (SARI). These drugs work by increasing the release and inhibiting the reuptake of serotonin in the synaptic space, thus increasing the effect of serotonin.

Example Question #3 : Neural Pharmacology

Aripiprazole is what class of drug? 

Possible Answers:

Selective serotonin re-uptake inhibitor (SSRI)

Atypical antipsychotic

Serotonin–norepinephrine reuptake inhibitor (SNRI)

Serotonin modulator and stimulator (SMS)

Correct answer:

Atypical antipsychotic

Explanation:

Aripiprazole is an atypical antipsychotic. It acts as a partial dopamine agonist and an agonist to multiple 5-HT (serotonin) receptors.

Example Question #4 : Neural Pharmacology

What class of drug is quetiapine?

Possible Answers:

Serotonin antagonist and reuptake inhibitor (SARI)

Norepinephrine reuptake inhibitor

Tricyclic antidepressant

Atypical antipsychotic

Correct answer:

Atypical antipsychotic

Explanation:

Quetiapine is classified as an atypical antipsychotic. Quetiapine is a powerful antihistamine and has pharmacological action at many receptor types: it is a serotonin, dopamine, and adrenergic antagonist.

Example Question #5 : Neural Pharmacology

Which of the following antidepressants is also used for smoking cessation?

Possible Answers:

Buspirone

Venlafaxine

Amitriptyline

Bupropion

Correct answer:

Bupropion

Explanation:

Bupropion is an antidepressant used for smoking cessation. None of the other medications listed are used for smoking cessation. 

Example Question #6 : Neural Pharmacology

Sertraline, paroxetine, and citalopram, are all classified as what type of antidepressant? 

Possible Answers:

Serotonin–norepinephrine reuptake inhibitors (SNRIs)

Serotonin modulator and stimulators (SMSs)

Monoamine oxidase inhibitors (MAOIs)

Selective serotonin re-uptake inhibitors (SSRIs)

Correct answer:

Selective serotonin re-uptake inhibitors (SSRIs)

Explanation:

Sertraline, paroxetine, and Citalopra are all selective serotonin re-uptake inhibitors (SSRIs). This class of drug works by blocking serotonin re-uptake in the synapse, thus increasing post-synaptic serotonin stimulation. They are one of the most widely used class of antidepressants in the United States and many parts of the world.

Example Question #7 : Neural Pharmacology

Zolpidem belongs in what drug class?

Possible Answers:

Orexin antagonist 

Selective serotonin re-uptake inhibitor (SSRI)

Nonbenzodiazepine hypnotic

Benzodiazepine

Correct answer:

Nonbenzodiazepine hypnotic

Explanation:

Zolpidem is a short acting nonbenzodiazepine hypnotic. It's actions are similar to benzodiazepine drugs in that it stimulates GABAa receptors at the same location as benzodiazepines. It is used in insomnia for initiating sleep, though it's short half life (3 hours) means it is not generally considered effective for maintaining sleep. 

Example Question #8 : Neural Pharmacology

All of the following are common anticonvulsants except __________.

Possible Answers:

lamotrigine

carbamazepine

valproate

risperidone

Correct answer:

risperidone

Explanation:

All of the answers given are common anticonvulsant medications except risperidone, which is a second generation atypical antipsychotic used in schizophrenia and bipolar disorder.

← Previous 1
Learning Tools by Varsity Tutors