Test: GRE Subject Test: Biochemistry, Cell, and Molecular Biology

1.

How do Bax and Bak promote cell death?

They allow the release of cytochrome c from the mitochondria into the cytosol, which activates procaspase

They cleave procaspase into caspase, which initiates the caspase cascade

They are a major component of the apoptosome

They bind and block Bcl2 from inhibiting Bax and Bak activators

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