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MCAT Chemical and Physical Foundations of Biological Systems Flashcards: 5e Enzyme Inhibition Regulation

Study 5e Enzyme Inhibition Regulation in MCAT Chemical and Physical Foundations of Biological Systems with focused flashcards that help you recognize the idea, recall the key rule, and apply it in practice-style prompts.

QUESTION

In Lineweaver–Burk plots, which inhibition type leaves the yy-intercept (1Vmax)\left(\frac{1}{V_{max}}\right) unchanged?

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ANSWER

Competitive inhibition. In Lineweaver-Burk plots, competitive inhibition increases the slope and x-intercept shift, but Vmax is unchanged, so y-intercept remains the same.

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MCAT Chemical and Physical Foundations of Biological Systems: Foundational Concepts

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This deck focuses on 5e Enzyme Inhibition Regulation, giving you a quick way to review the definitions, rules, and examples that matter most for MCAT Chemical and Physical Foundations of Biological Systems.

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Practice questions

1 of 50Practice questions for this set
A mitochondrial enzyme is assayed for conversion of substrate S to product P. Baseline: Km=0.25 mMK_m = 0.25\ \text{mM}, Vmax=30 μM min−1V_{max} = 30\ \mu\text{M}\,\text{min}^{-1}. Inhibitor M increases Km,appK_m,app to 1.0 mM1.0\ \text{mM} with VmaxV_{max} unchanged, while inhibitor N decreases Vmax,appV_{max,app} to 15 μM min−115\ \mu\text{M}\,\text{min}^{-1} with KmK_m unchanged. Which statement best describes how increasing [S] would differentially affect inhibition by M versus N?
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