Pharmacokinetics

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NCLEX-PN › Pharmacokinetics

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1

A client with a history of chronic stable angina takes nitroglycerine when needed for an acute attack. Which of the following is not associated with the administration of nitroglycerine?

The mechanism of action involves increase in cardiac contractility

To prevent degradation, nitroglycerine should be kept in a closed dark bottle.

The medication relieves pain within 3 minutes and provides relief for up to one hour

Nitroglycerine can be taken sublingually by tablet or metered spray

The patient may experience orthostatic hypotension

Explanation

Nitroglycerine is a short acting nitrate. This class of medication works by relaxing arterial and venous smooth muscle promoting vasodilation. This medication does not improve cardiac contractility.

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