Metoclopramide is an antiemetic and gastroprokinetic agent commonly used to treat nausea and vomiting, to facilitate gastric emptying in people with gastroparesis, and as a treatment for the gastric stasis often associated with migraine headaches.

5-fluouracil is a fluoropyrimidine analog which inhibits translation, synthesis, and function of RNA and DNA, thus slowing down cellular metabolism. It is used in treatment of colorectal, breast, and ovarian cancer, in addition to cancers of the GI and head and neck.