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NAPLEX Flashcards: Primary Literature Evaluation

Study Primary Literature Evaluation in NAPLEX with focused flashcards that help you recognize the idea, recall the key rule, and apply it in practice-style prompts.

QUESTION

What does it imply when a 95%95\% CI for a risk ratio includes 11?

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ANSWER

Not statistically significant at α=0.05\alpha=0.05. Inclusion of 1 in the 95%95\% CI for RR suggests no significant difference between groups, as it encompasses no effect.

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NAPLEX: Foundational Knowledge For Pharmacy Practice

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This deck focuses on Primary Literature Evaluation, giving you a quick way to review the definitions, rules, and examples that matter most for NAPLEX.

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Work through these flashcards in short sessions. Try to answer each prompt before flipping the card, then revisit any cards you miss until the explanation feels automatic.

Practice questions

1 of 36Practice questions for this set
A 58-year-old man (92 kg) with type 2 diabetes has persistent albuminuria (urine albumin-to-creatinine ratio 420 mg/g) despite lisinopril 20 mg daily; estimated glomerular filtration rate (eGFR) is 48 mL/min/1.73 m2^2 and potassium is 4.6 mEq/L. You review a randomized, double-blind, placebo-controlled trial in adults with type 2 diabetes, eGFR 25–75, and albuminuria on maximally tolerated angiotensin-converting enzyme inhibitor or angiotensin receptor blocker: finerenone 20 mg daily (10 mg if eGFR 25–60) vs placebo for a median 2.6 years; the primary composite kidney outcome (kidney failure, sustained ≥40% eGFR decline, or renal death) occurred in 17.8% vs 21.1% (hazard ratio 0.82; 95% confidence interval 0.73–0.93; p=0.001), with hyperkalemia leading to discontinuation in 2.3% vs 0.9%. Based on the study, which treatment is most appropriate for this patient?
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