Nuclear Decay and Radioactivity (4E)

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MCAT Chemical and Physical Foundations of Biological Systems › Nuclear Decay and Radioactivity (4E)

Questions 1 - 10
1

A laboratory calibrates a $^{99\text{m}}\text{Tc}$ generator used for SPECT imaging. The isomeric transition is $^{99\text{m}}\text{Tc} \rightarrow ,^{99}\text{Tc} + \gamma$. The half-life is listed as 6.0 h. Based on the decay model, what prediction can be made about the decay rate over time in a sealed vial?

The activity remains constant because gamma emission does not change the nucleus

The activity increases with time because $^{99\text{m}}\text{Tc}$ accumulates as $^{99}\text{Tc}$ decays

The activity decreases exponentially with time because the decay probability per nucleus is constant

The activity decreases linearly with time because a constant amount decays each hour

Explanation

This question tests understanding of radioactive decay kinetics and activity over time. Radioactive decay follows first-order kinetics, where the activity A(t) = A₀e^(-λt), showing exponential decrease over time. The decay probability per nucleus remains constant (λ), leading to exponential rather than linear decay behavior. For ⁹⁹ᵐTc with a 6.0 h half-life, the activity will decrease to half its initial value every 6.0 hours. Choice A correctly identifies the exponential decay pattern due to constant decay probability. Choices B and C incorrectly suggest linear decay or constant activity, while choice D impossibly suggests increasing activity. When evaluating decay patterns, remember that radioactive decay always follows exponential kinetics with constant decay probability per nucleus.

2

A laboratory prepares a sealed standard containing $^{60}\text{Co}$, which decays by $\beta^-$ emission to an excited state of $^{60}\text{Ni}$ followed by gamma emission. The half-life of $^{60}\text{Co}$ is 5.27 y. Based on the decay model, what outcome is most likely regarding the sequence of emissions?

Gamma emission must occur before beta emission because photons are faster than electrons

Gamma emission changes the element, and subsequent beta emission relaxes the nucleus without changing identity

Beta emission decreases mass number by 4, and gamma emission decreases mass number by 1

Beta emission changes the element, and subsequent gamma emission relaxes the daughter nucleus without changing its identity

Explanation

This question tests understanding of sequential nuclear decay processes. In ⁶⁰Co decay, β- emission occurs first, converting ⁶⁰Co to ⁶⁰Ni* (excited state) by changing a neutron to proton, thus changing the element. The excited ⁶⁰Ni* then undergoes gamma decay to ground state ⁶⁰Ni, releasing energy without changing nuclear composition. Choice A correctly describes beta emission changing the element followed by gamma emission relaxing the daughter nucleus. Choice B reverses the sequence impossibly, choice C gives incorrect mass changes, and choice D incorrectly relates emission order to particle speed. When analyzing decay chains, beta decay changes element identity while subsequent gamma decay only changes energy state.

3

In a nuclear medicine imaging protocol, a patient receives an intravenous dose of $^{18}\text{F}$-FDG. The radionuclide undergoes $\beta^+$ decay: $^{18}\text{F} \rightarrow ,^{18}\text{O} + e^+ + \nu_e$. The decay constant is reported as $\lambda = 1.05\times 10^{-4}\ \text{s}^{-1}$. Based on this decay model, what outcome is most likely at the nuclear level?

The mass number decreases by 4 because an alpha particle is emitted from the nucleus

The atomic number increases by 1 because a neutron converts to a proton, producing an electron

The atomic number decreases by 1 because a proton converts to a neutron, producing a positron

The nucleus remains the same isotope because only a gamma photon is emitted

Explanation

This question tests understanding of nuclear decay and radioactivity, specifically beta-plus decay. In β+ decay, a proton in the nucleus converts to a neutron, emitting a positron (e+) and a neutrino (νe), which decreases the atomic number by 1 while the mass number remains constant. For ¹⁸F → ¹⁸O + e+ + νe, fluorine (Z=9) transforms to oxygen (Z=8), confirming the atomic number decreases by 1. Choice A correctly describes this process where a proton converts to a neutron with positron emission. Choice B incorrectly describes alpha decay, choice C describes β- decay (opposite process), and choice D describes gamma decay. When analyzing nuclear decay, verify that charge and mass numbers are conserved on both sides of the equation.

4

A research lab labels antibodies with $^{131}\text{I}$ for a targeted therapy model. Assume $^{131}\text{I}$ undergoes $\beta^-$ decay to $^{131}\text{Xe}$. The decay constant is $\lambda = 1.0\times 10^{-6}\ \text{s}^{-1}$. Based on the decay model, what is most consistent with conservation laws for the nuclear reaction?

Mass number increases by 1 and atomic number decreases by 1, with a positron emitted

Mass number decreases by 4 and atomic number decreases by 2, with an alpha particle emitted

Mass number remains 131 and atomic number increases by 1, with an electron emitted

Mass number decreases by 1 and atomic number remains constant, with a neutron emitted

Explanation

This question tests understanding of beta-minus decay and conservation laws. In β- decay of ¹³¹I to ¹³¹Xe, a neutron converts to a proton: n → p + e- + ν̄e. This increases atomic number from 53 (iodine) to 54 (xenon) while mass number remains 131, conserving baryon number. An electron is emitted to conserve charge. Choice A correctly describes mass number conservation at 131, atomic number increase by 1, and electron emission. Choice B incorrectly suggests neutron emission, choice C describes alpha decay, and choice D is physically impossible. When verifying nuclear reactions, check that mass number, charge, and baryon number are conserved on both sides of the equation.

5

A patient receives a therapeutic radionuclide that decays by alpha emission. The clinician notes that alpha particles have high linear energy transfer and short range in tissue. Which statement best describes what must be true about the nuclear change in alpha decay?

The nucleus loses 1 proton and gains 1 neutron, decreasing atomic number by 1 with no mass change

The nucleus loses 2 protons and 2 neutrons, decreasing atomic number by 2 and mass number by 4

The nucleus remains unchanged because alpha particles are emitted from the electron cloud

The nucleus gains 2 protons and 2 neutrons, increasing atomic number by 2 and mass number by 4

Explanation

This question tests understanding of alpha decay and its nuclear changes. Alpha particles are helium-4 nuclei (²He⁴) containing 2 protons and 2 neutrons. When emitted, the parent nucleus loses these 4 nucleons, decreasing atomic number by 2 and mass number by 4. This explains alpha particles' high mass and charge, leading to high linear energy transfer and short tissue range. Choice A correctly describes the loss of 2 protons and 2 neutrons with corresponding decreases in atomic and mass numbers. Choice B incorrectly suggests gaining nucleons, choice C describes a different process, and choice D incorrectly places alpha emission outside the nucleus. When analyzing alpha decay, remember the emitted particle is a complete helium nucleus.

6

A radiotherapy seed contains $^{125}\text{I}$, which decays by electron capture (EC): $^{125}\text{I} + e^- \rightarrow ,^{125}\text{Te} + \nu_e$ (followed by characteristic photons). The decay constant is $\lambda = 1.46\times 10^{-7}\ \text{s}^{-1}$. Which statement best describes the decay process illustrated?

The nucleus emits a helium nucleus, decreasing mass number by 4 and atomic number by 2

A proton converts to a neutron, decreasing the atomic number by 1 while mass number stays the same

The nucleus emits an electron, decreasing the atomic number by 1 and the mass number by 1

A neutron converts to a proton, increasing the atomic number by 1 while mass number stays the same

Explanation

This question tests understanding of electron capture (EC) as a mode of nuclear decay. In electron capture, an inner orbital electron is captured by a proton in the nucleus, converting it to a neutron: p + e- → n + νe, which decreases the atomic number by 1 while mass number stays constant. For ¹²⁵I + e- → ¹²⁵Te + νe, iodine (Z=53) captures an electron to become tellurium (Z=52), confirming the atomic number decreases by 1. Choice A correctly describes this process where a proton converts to a neutron. Choice B incorrectly describes β- decay, choice C describes alpha decay, and choice D incorrectly suggests mass number changes. When analyzing electron capture, remember it's functionally similar to β+ decay in terms of nuclear transformation but involves capturing an existing electron rather than emitting a positron.

7

A PET tracer sample contains $^{18}\text{F}$ with half-life 110 min. The sample is transported for 220 min before use. Based on the decay model, what outcome is most likely for the remaining activity (ignoring biological clearance)?

About 12.5% remains because three half-lives have elapsed

About 75% remains because two half-lives remove only one quarter

About 25% remains because two half-lives have elapsed

About 50% remains because half-life depends on initial activity

Explanation

This question tests understanding of radioactive decay over multiple half-lives. With t₁/₂ = 110 min and transport time = 220 min, exactly 2 half-lives have elapsed (220/110 = 2). After one half-life, 50% remains; after two half-lives, 25% remains. The formula is: fraction remaining = (1/2)^(t/t₁/₂) = (1/2)² = 1/4 = 25%. Choice A correctly identifies that 25% remains after two half-lives. Choice B incorrectly ignores time dependence, choice C miscalculates the fraction, and choice D incorrectly counts three half-lives. When calculating remaining activity, always determine the number of half-lives as t/t₁/₂ and apply $(1/2)^n$.

8

An environmental monitoring station tracks radon-222 ($^{222}\text{Rn}$) in a basement. $^{222}\text{Rn}$ undergoes alpha decay: $^{222}\text{Rn} \rightarrow ,^{218}\text{Po} + ,^{4}\text{He}$. The half-life is 3.8 d. Which statement best describes the decay process illustrated?

The daughter has mass number 221 and atomic number decreased by 1 relative to the parent

The daughter has mass number 222 and atomic number increased by 1 relative to the parent

The daughter has mass number 218 and atomic number decreased by 2 relative to the parent

The daughter is the same isotope because alpha particles carry no nucleons

Explanation

This question tests understanding of alpha decay and its effect on nuclear composition. In alpha decay, the nucleus emits an alpha particle (⁴He), which contains 2 protons and 2 neutrons, decreasing the mass number by 4 and atomic number by 2. For ²²²Rn → ²¹⁸Po + ⁴He, radon (Z=86) loses an alpha particle to become polonium (Z=84), with mass decreasing from 222 to 218. Choice A correctly describes the daughter having mass number 218 and atomic number decreased by 2. Choice B incorrectly suggests atomic number increase, choice C gives wrong mass change, and choice D incorrectly claims alpha particles carry no nucleons. When analyzing alpha decay, always subtract 4 from mass number and 2 from atomic number.

9

A sealed vial contains $N_0$ nuclei of a medical tracer that decays with half-life 4.0 h. No tracer is added or removed. Based on the decay model, what outcome is most likely after 12 h?

Approximately $N_0/16$ nuclei remain because four half-lives have elapsed

Approximately $N_0/3$ nuclei remain because decay is linear in time

Approximately $N_0/8$ nuclei remain because three half-lives have elapsed

Approximately $N_0/2$ nuclei remain because only one half-life has elapsed

Explanation

This question tests understanding of radioactive decay over multiple half-lives. After one half-life (4.0 h), N₀/2 nuclei remain; after two half-lives (8.0 h), N₀/4 remain; after three half-lives (12.0 h), N₀/8 remain. The general formula is N(t) = N₀(1/2)^(t/t₁/₂). With t = 12 h and t₁/₂ = 4.0 h, we have N(12) = N₀(1/2)³ = N₀/8. Choice A correctly identifies that three half-lives have elapsed, leaving N₀/8 nuclei. Choice B incorrectly assumes linear decay, choice C miscounts half-lives, and choice D overcounts to four half-lives. When calculating decay over time, always determine the number of half-lives elapsed as t/t₁/₂.

10

A lab measures the activity of a sealed gamma source used to calibrate a detector. The source has half-life 30.0 y. Based on the decay model, what prediction can be made about the decay constant $\lambda$ (in $\text{y}^{-1}$) relative to a different source with half-life 5.0 y?

Both sources have the same $\lambda$ because decay constants are universal

The 30.0-y source has a smaller $\lambda$ because it decays more slowly

The 30.0-y source has $\lambda=0$ because long half-life implies stability

The 30.0-y source has a larger $\lambda$ because it decays more slowly

Explanation

This question tests understanding of the relationship between half-life and decay constant. The decay constant λ = ln(2)/t₁/₂, so longer half-life means smaller decay constant. For the 30.0-y source: λ = 0.693/30.0 ≈ 0.0231 y⁻¹; for the 5.0-y source: λ = 0.693/5.0 ≈ 0.139 y⁻¹. The 30.0-y source has a smaller λ because it decays more slowly. Choice B correctly identifies that longer half-life corresponds to smaller decay constant. Choice A reverses the relationship, choice C incorrectly claims universal constants, and choice D incorrectly suggests λ=0 for long-lived isotopes. When comparing decay constants, remember that λ and t₁/₂ are inversely related.

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