Principles of Bioenergetics and Thermodynamics (1D) Practice Test

A metabolic reaction releases heat to the surroundings ($\Delta H<0$) but is observed to be nonspontaneous in the forward direction under the tested conditions ($\Delta G>0$). Which conclusion is most consistent with $\Delta G=\Delta H-T\Delta S$?

A cell drives an endergonic biosynthetic reaction by rapidly removing its product via sequestration into a vesicle. Which prediction is most consistent with the effect on $\Delta G$ for the biosynthetic reaction (with $\Delta G = \Delta G^\circ' + RT\ln Q$)?