Non-Mendelian Genetics
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AP Biology › Non-Mendelian Genetics
In a fish species, scale color shows codominance. Allele G produces green scales and allele S produces silver scales. Heterozygotes (GS) have both green and silver scales visible. Two heterozygous fish are crossed (GS × GS). Which outcome best predicts the phenotypes among their offspring?
About 50% green and 50% silver, because heterozygotes split into parental phenotypes.
All offspring green-and-silver, because codominant alleles always remain paired.
All offspring silver, because S alleles are more common in heterozygous parents.
About 75% green and 25% silver, because green is completely dominant to silver.
About 25% green, 50% green-and-silver, 25% silver, because genotypes follow a 1:2:1 ratio.
Explanation
This question assesses the skill of analyzing non-Mendelian inheritance patterns, specifically codominance in fish scale color. Both parents are heterozygous GS, contributing G or S alleles, leading to a Punnett square with 25% GG (green), 50% GS (green-and-silver), and 25% SS (silver). Codominance causes both scale colors to appear in heterozygotes, producing the mixed phenotype. The 1:2:1 ratio reflects independent segregation of alleles in this cross. Choice D is tempting but wrong as it assumes heterozygotes split into pure phenotypes, a misconception confusing codominance with blending or dominance. To handle codominance, use Punnett squares and remember that both alleles express equally in heterozygotes.
A human blood type gene has three alleles: $I^A$, $I^B$, and $i$. Alleles $I^A$ and $I^B$ are codominant, and both are dominant to $i$. A person with type AB blood ($I^AI^B$) has a child with a person with type O blood ($ii$). Which set of possible child blood types is expected?
Only A, B, and O
Only A, B, and AB
Only A and B
Only AB and O
All four types: A, B, AB, and O
Explanation
This problem involves analyzing non-Mendelian inheritance with codominant alleles in human blood types. The AB parent $(I^A$ $I^B$) can contribute either $I^A$ or $I^B$, while the O parent (ii) can only contribute i. The possible offspring genotypes are $I^A$ i (type A blood) and $I^B$ i (type B blood), each with 50% probability. This makes answer B correct, as children can only have type A or B blood. Students often mistakenly include AB as a possibility (answer C), forgetting that the O parent cannot contribute $I^A$ or $I^B$ alleles. The key strategy is to recognize that each parent contributes one allele and that the O parent (ii) can only pass on the recessive i allele.
In a rabbit population, coat color is controlled by multiple alleles at one locus with a dominance hierarchy: C (full color) > $c^ch$ (chinchilla) > $c^h$ (Himalayan) > c (albino). A chinchilla rabbit with genotype $c^ch$ c is crossed with a Himalayan rabbit with genotype $c^h$ c. Assuming simple dominance by the hierarchy, which offspring phenotype is expected to be most common?
Himalayan, because $c^h$ is dominant to $c^ch$ and c
Full color, because C will appear in half the offspring
Albino, because recessive alleles combine in most offspring
Chinchilla, because $c^ch$ is dominant to $c^h$ and c
All phenotypes occur equally because there are four alleles
Explanation
This question assesses the skill of analyzing non-Mendelian inheritance patterns, specifically multiple alleles with a dominance hierarchy in rabbit coat color. The chinchilla rabbit is $c^ch$ c, producing $c^ch$ or c gametes, and the Himalayan is $c^h$ c, producing $c^h$ or c gametes. Offspring genotypes are $c^ch$ $c^h$ (chinchilla, since $c^ch$ > $c^h$), $c^ch$ c (chinchilla, $c^ch$ > c), $c^h$ c (Himalayan, $c^h$ > c), and c c (albino), with chinchilla in 50% of cases. This matches choice B, as $c^ch$ dominates over both $c^h$ and c in the hierarchy. A tempting distractor is choice D, predicting mostly albino by ignoring the hierarchy, a misconception treating all alleles as equally recessive. For a transferable strategy, always reference the dominance order when predicting phenotypes in multiple-allele systems and count frequencies accordingly.
In a bird species, feather color shows incomplete dominance: allele B yields black, allele W yields white, and BW heterozygotes are gray. A gray bird (BW) is crossed with a white bird (WW). Which outcome best predicts the offspring phenotypes?
Three-fourths gray and one-fourth white
All offspring are black
Half the offspring are black and half are white
Half the offspring are gray and half are white
All offspring are gray
Explanation
This question examines non-Mendelian inheritance through incomplete dominance in bird feather color. The gray bird (BW) can contribute either B or W alleles, while the white bird (WW) can only contribute W. The possible offspring genotypes are BW (gray) and WW (white) in equal proportions, resulting in half gray and half white offspring. Choice C incorrectly applies simple dominance thinking with a 3:1 ratio, but incomplete dominance produces distinct phenotypes for each genotype. To solve incomplete dominance crosses, identify the possible gametes from each parent and remember that heterozygotes have an intermediate phenotype distinct from both homozygotes.
In a certain fish, scale color is controlled by multiple alleles at one locus. Allele G produces gold scales, allele S produces silver scales, and allele g produces no reflective pigment. G and S are codominant to each other, and both are dominant over g. A fish with genotype Gg is crossed with a fish with genotype Sg. Which offspring phenotype is expected to occur at a frequency of 25%?
No reflective pigment
Gold only
Silver only
Gold-and-silver (both colors visible)
All offspring show gold-and-silver
Explanation
This question assesses the skill of analyzing non-Mendelian inheritance patterns, specifically multiple alleles with codominance in fish scale color. The Gg fish produces G or g gametes, and the Sg fish produces S or g gametes, yielding GS, Gg, Sg, and gg offspring each at 25%. The gg genotype lacks reflective pigment since g is recessive to both G and S, matching the no pigment phenotype. This matches choice D, as one-quarter of offspring are gg with this phenotype. A tempting distractor is choice C, assuming gold-and-silver for 25% by misidentifying gg as codominant, a misconception confusing recessivity with codominance. A transferable strategy is to list all genotype combinations and apply the dominance rules to predict phenotype frequencies accurately.
In a plant species, leaf shape shows incomplete dominance. Allele L produces long leaves, and allele l produces round leaves. LL plants have long leaves, ll plants have round leaves, and Ll plants have intermediate leaves. Two intermediate-leaf plants are crossed. Assuming a single autosomal gene, which phenotypic ratio is expected among the offspring?
3 long : 1 round
2 long : 1 intermediate : 1 round
1 intermediate : 1 round
1 long : 2 intermediate : 1 round
All intermediate
Explanation
This question assesses the skill of analyzing non-Mendelian inheritance patterns, specifically incomplete dominance in plant leaf shape. Both parents are heterozygous Ll, showing intermediate leaves, and each contributes L or l equally in gametes. The cross yields 25% LL (long), 50% Ll (intermediate), and 25% ll (round), producing a 1:2:1 phenotypic ratio. This matches choice B, as incomplete dominance results in a distinct heterozygous phenotype without blending into dominance. A tempting distractor is choice A, predicting a 3:1 ratio by assuming complete dominance, a misconception that applies Mendelian rules to non-Mendelian traits. For similar questions, use Punnett squares to visualize ratios and remember that incomplete dominance often yields three phenotypes in heterozygous crosses.
In cattle, coat color shows codominance. Allele $C^R$ produces red hairs and allele $C^W$ produces white hairs. $C^RC$^R cattle are red, $C^WC$^W cattle are white, and $C^RC$^W cattle are roan (both red and white hairs). A rancher crosses a roan bull with a white cow $(C^RC$^W × $C^WC$^W). Which offspring phenotype ratio is most likely?
All offspring are roan because both alleles are expressed
Half red and half white offspring
All offspring are white because $C^W$ is dominant
Half roan and half white offspring
Three-fourths roan and one-fourth white offspring
Explanation
This question requires analyzing non-Mendelian inheritance through codominance in cattle coat color. In codominance, both alleles in a heterozygote are fully expressed simultaneously, resulting in roan cattle $(C^RC$^W) that have both red and white hairs. When crossing a roan bull $(C^RC$^W) with a white cow $(C^WC$^W), we can predict offspring using a Punnett square: the roan parent can contribute either $C^R$ or $C^W$, while the white parent can only contribute $C^W$. This produces offspring that are 50% $C^RC$^W (roan) and 50% $C^WC$^W (white), giving a 1:1 ratio. Students often incorrectly choose option A, thinking codominance means all offspring express both traits, but this ignores the white parent's homozygous genotype. When solving codominance problems, remember that both alleles are expressed in heterozygotes, but offspring ratios still depend on parental genotypes.
In cattle, coat color shows codominance. Allele $C^R$ produces red hairs and allele $C^W$ produces white hairs. $C^R$ $C^R$ cattle are red, $C^W$ $C^W$ cattle are white, and $C^R$ $C^W$ cattle are roan (both red and white hairs visible). A roan bull is crossed with a red cow. Assume a single autosomal gene. Which offspring phenotype ratio is expected from this cross?
3 red : 1 roan
3 roan : 1 red
1 red : 1 white
1 red : 1 roan
All roan
Explanation
This question assesses the skill of analyzing non-Mendelian inheritance patterns, specifically codominance in cattle coat color. The roan bull is $C^R$ $C^W$, expressing both red and white hairs due to codominance, and the red cow is $C^R$ $C^R$, producing only red hairs. Crossing these yields offspring where half inherit $C^R$ from both parents (red) and half inherit $C^R$ from the bull and $C^W$ from the cow (roan), resulting in a 1:1 ratio. This matches choice A, as codominance allows both alleles to be visible in heterozygotes without blending. A tempting distractor is choice D, assuming all offspring are roan due to misunderstanding codominance as incomplete dominance, a misconception that ignores the equal expression of both alleles. For transferable strategy, identify codominance by checking if heterozygotes show both parental traits distinctly, then apply standard Punnett square analysis.
In a cat species, fur pattern is X-linked. Allele $X^O$ produces orange fur and allele $X^o$ produces black fur. Heterozygous females $(X^O$ $X^o$) show patches of orange and black. A patchy female is crossed with a black male $(X^o$ Y). Assume no other genes affect color. Which outcome best predicts the phenotypes of male offspring?
All male offspring are black
Half the male offspring are orange and half are black
Male offspring phenotypes depend only on the father’s X allele
All male offspring are patchy
Three-fourths of male offspring are orange and one-fourth are black
Explanation
This question assesses the skill of analyzing non-Mendelian inheritance patterns, specifically X-linked traits in cats. The patchy female is $X^O$ $X^o$, contributing $X^O$ or $X^o$ to sons, while the black male is $X^o$ Y, contributing Y to sons. Male offspring (XY) are thus 50% $X^O$ Y (orange) and 50% $X^o$ Y (black), with no patchy pattern possible in males due to single X. This matches choice B, reflecting the equal inheritance from the heterozygous mother. A tempting distractor is choice C, predicting all black males by assuming the father's allele dominates, a misconception ignoring that sons inherit their X from the mother only. For transferable strategy, focus on X inheritance from the mother for male phenotypes in X-linked traits and calculate ratios based on her genotype.
Human ABO blood type is controlled by three alleles: $I^A$, $I^B$, and $i$. $I^A$ and $I^B$ are codominant, and both are dominant to $i$. A person with type AB ($I^A I^B$) has a child with a person with type O ($ii$). Which blood type(s) can their child have?
Only type A or type B
Only type A
Only type O
Type A, type B, type AB, or type O
Only type AB
Explanation
This question tests analysis of non-Mendelian inheritance involving multiple alleles and codominance in human ABO blood types. The AB parent $(I^A$ $I^B$) can contribute either $I^A$ or $I^B$, while the O parent (ii) can only contribute i. The possible offspring genotypes are $I^A$ i (type A) and $I^B$ i (type B), with equal probability. Choice D incorrectly suggests all blood types are possible, but this cross cannot produce type AB (requires both $I^A$ and $I^B$) or type O (requires ii). When solving ABO blood type problems, systematically determine which alleles each parent can contribute and remember that i is recessive to both $I^A$ and $I^B$.