The medial malleolus is located on the inferiomedial aspect of the tibia. The fibula is on the lateral aspect of the lower limb. The talus and calcaneus are in the foot. The femur is in the upper portion of the leg.

Sesamoid bones are located in tendons or joint capsules. They reduce friction, increase the force the tendon can pull, and/or maintain the shape of tendons when they are taut. The largest sesamoid bone in the body is the patella. The pisiform is also a sesamoid bone, but is much smaller than the patella and is located in the wrist. The scaphoid and hamate are located in the wrist, but are not sesamoid.

Anatomical definitions determine the thigh to be the region between the knee and hip, and the leg to be the region between the knee and ankle. The thigh houses the femur, while the leg houses the tibia and fibula. The fibula articulates with the talus, one of the seven bones found in the ankle, at its distal end and the femur at its proximal end. This distal articulation is part of the ankle joint, while the proximal articulation is part of the knee joint.

The tibia is the larger bone of the two, and is responsible for carrying the majority of the weight of the lower limb.

Anatomical definitions determine the thigh to be the region between the knee and hip, and the leg to be the region between the knee and ankle. The thigh houses the femur, while the leg houses the tibia and fibula. The fibula articulates with the talus, one of the seven bones found in the ankle, at its distal end and the femur at its proximal end. This distal articulation is part of the ankle joint, while the proximal articulation is part of the knee joint.

The tibia is the larger bone of the two, and is responsible for carrying the majority of the weight of the lower limb.

The third cuneiform articulates with the navicular, second cuneiform, cuboid, and second, third, and fourth metatarsals.

The popliteal fossa is part of the femur. The lateral supracondylar line is also part of the femur. The soleal line is part of the tibia. The the subclavian groove is part of the clavicle and is an attachment site for the subclavius muscle.

The third cuneiform articulates with the navicular, second cuneiform, cuboid, and second, third, and fourth metatarsals.

Sesamoid bones are located in tendons or joint capsules. They reduce friction, increase the force the tendon can pull, and/or maintain the shape of tendons when they are taut. The largest sesamoid bone in the body is the patella. The pisiform is also a sesamoid bone, but is much smaller than the patella and is located in the wrist. The scaphoid and hamate are located in the wrist, but are not sesamoid.

The medial malleolus is located on the inferiomedial aspect of the tibia. The fibula is on the lateral aspect of the lower limb. The talus and calcaneus are in the foot. The femur is in the upper portion of the leg.

The popliteal fossa is part of the femur. The lateral supracondylar line is also part of the femur. The soleal line is part of the tibia. The the subclavian groove is part of the clavicle and is an attachment site for the subclavius muscle.