Preventive Care And Screening

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USMLE Step 3 › Preventive Care And Screening

Questions 1 - 10
1

History & Lifestyle: 50-year-old man here for routine check-up. • Smokes 1 pack/day x 25 years. • Works desk job; no regular exercise. • BMI 29; waist circumference increased. • Diet high in saturated fat. • No known diabetes. Family History: Brother had MI at 52; father had stroke at 60. Preventive Care Review: No lipid testing in >10 years; no statin therapy. BP today 132/84. He asks what screening is needed to reduce cardiovascular risk. Exam is normal. Clinician counsels on smoking cessation, weight loss, and physical activity. Guidelines support primary prevention risk stratification using standard labs.

What is the next best step in preventive care for this patient?

Order coronary CT angiography screening

Order BNP level for heart failure screening

Order troponin to assess silent ischemia

Order fasting lipid profile for ASCVD risk

Explanation

This question tests understanding of preventive care and screening in primary care (USMLE Step 3). Preventive care involves applying evidence-based guidelines to recommend appropriate screenings and lifestyle modifications. In this vignette, the 50-year-old man has cardiovascular risk factors and no recent lipid testing, the recommended step is ordering a fasting lipid profile for ASCVD risk, aligning with ACC-AHA guidelines. Choice A is correct because it matches ACC-AHA recommendations for lipid screening in adults with risk factors to assess 10-year ASCVD risk. Choice B is incorrect because it suggests coronary CT angiography, which is not routinely recommended for primary prevention screening without symptoms. For teaching, emphasize the importance of staying updated with guidelines, identifying patient-specific risk factors, and prioritizing screenings that provide the greatest benefit. Encourage students to practice applying guidelines in varied scenarios to build confidence in clinical decision-making.

2

What is the most appropriate recommendation regarding zoster vaccination?

She should receive the live attenuated zoster vaccine for better immunity.

She is not eligible for any zoster vaccine due to her methotrexate use.

She should receive the recombinant zoster vaccine series.

She must temporarily discontinue methotrexate before receiving the vaccine.

Explanation

The Advisory Committee on Immunization Practices (ACIP) recommends the recombinant zoster vaccine (Shingrix) for all immunocompetent adults aged 50 and older, including those on low-dose immunosuppressive therapy such as methotrexate (≤0.4 mg/kg/week). The recombinant vaccine is not a live virus and is safe and effective in this population. The live attenuated vaccine would be contraindicated.

3

History & Lifestyle: 50-year-old man for preventive visit. • Smokes 1 pack/day; sedentary; BMI 32. • No history of diabetes; last glucose unknown. Family History: Mother with type 2 diabetes; father MI at 57. Preventive Care Review: BP 136/88. No labs in years. He asks about diabetes screening. No symptoms of hyperglycemia.

Based on the vignette, which screening test is recommended for this patient?

Screen with random insulin level annually

Screen for type 2 diabetes with HbA1c

Screen for type 1 diabetes with autoantibodies

No diabetes screening until symptoms develop

Explanation

This question tests understanding of preventive care and screening in primary care (USMLE Step 3). Preventive care involves applying evidence-based guidelines to recommend appropriate screenings and lifestyle modifications. In this vignette, the 50-year-old obese man with risk factors asks about diabetes screening, the recommended test is screening for type 2 diabetes with HbA1c, aligning with USPSTF guidelines. Choice A is correct because it matches USPSTF recommendations for screening adults aged 35-70 who are overweight or obese. Choice C is incorrect because it suggests no screening until symptoms, ignoring asymptomatic detection benefits. For teaching, emphasize the importance of staying updated with guidelines, identifying patient-specific risk factors, and prioritizing screenings that provide the greatest benefit. Encourage students to practice applying guidelines in varied scenarios to build confidence in clinical decision-making.

4

History & Lifestyle: 25-year-old woman for wellness visit. • Sexually active with multiple partners; inconsistent condom use. • No prior HIV test. • No injection drug use. • No symptoms. Family History: Noncontributory. Preventive Care Review: Vaccines reviewed; Pap up to date. She asks if HIV testing is recommended without symptoms.

Based on the vignette, which screening test is recommended for this patient?

No HIV screening unless symptomatic

One-time HIV Ag/Ab screening test

HIV viral load screening every 6 months

CD4 count screening without HIV diagnosis

Explanation

This question tests understanding of preventive care and screening in primary care (USMLE Step 3). Preventive care involves applying evidence-based guidelines to recommend appropriate screenings and lifestyle modifications. In this vignette, the 25-year-old woman with multiple partners has no prior HIV test, the recommended screening is one-time HIV Ag/Ab test, aligning with USPSTF guidelines. Choice A is correct because it matches USPSTF recommendations for screening all adults aged 15-65 at least once. Choice D is incorrect because it suggests no screening unless symptomatic, ignoring routine recommendations. For teaching, emphasize the importance of staying updated with guidelines, identifying patient-specific risk factors, and prioritizing screenings that provide the greatest benefit. Encourage students to practice applying guidelines in varied scenarios to build confidence in clinical decision-making.

5

History & Lifestyle: 10-year-old boy for annual well-child check. • Parents report no concerns about school performance. • Screen time ~4 hours/day; limited physical activity. • Drinks soda daily. Family History: Noncontributory. Preventive Care Review: Immunizations current. Physical exam: BMI 95th percentile. Development: normal language and social skills.

Which lifestyle modification should be prioritized in this scenario?

Begin intermittent fasting without supervision

Start high-protein diet to promote weight loss

Increase daily physical activity and reduce screen time

Restrict all dietary fat to zero grams

Explanation

This question tests understanding of preventive care and screening in primary care (USMLE Step 3). Preventive care involves applying evidence-based guidelines to recommend appropriate screenings and lifestyle modifications. In this vignette, the 10-year-old boy has BMI at 95th percentile with excessive screen time and soda intake, the prioritized modification is increasing daily physical activity and reducing screen time, aligning with AAP guidelines. Choice A is correct because it matches AAP recommendations for at least 60 minutes of activity daily and limiting screen time to reduce obesity risk. Choice D is incorrect because it suggests restricting all dietary fat, which is not balanced or recommended. For teaching, emphasize the importance of staying updated with guidelines, identifying patient-specific risk factors, and prioritizing screenings that provide the greatest benefit. Encourage students to practice applying guidelines in varied scenarios to build confidence in clinical decision-making.

6

History & Lifestyle: 70-year-old woman with hypertension presents for routine follow-up and preventive care. • Medications: amlodipine 10 mg daily, lisinopril 20 mg daily; adherent. • Home BP averages 128/76. • Walks 20 minutes 3x/week; diet moderate sodium. • Never smoker; drinks 1 glass wine weekly. Family History: Mother had hip fracture at 78. Preventive Care Review: No prior bone density testing; no chronic glucocorticoid use. No falls in past year. Physical exam: BMI 23, steady gait.

Based on the vignette, which screening test is recommended for this patient?

Whole-body CT for fracture risk

DXA scan for osteoporosis screening

Bone scan annually regardless of risk

Routine serum vitamin D screening only

Explanation

This question tests understanding of preventive care and screening in primary care (USMLE Step 3). Preventive care involves applying evidence-based guidelines to recommend appropriate screenings and lifestyle modifications. In this vignette, the 70-year-old woman has no prior bone density testing, the recommended screening is DXA scan for osteoporosis, aligning with USPSTF guidelines. Choice A is correct because it matches USPSTF recommendations for osteoporosis screening in women aged 65 and older. Choice B is incorrect because it suggests whole-body CT, which is not indicated for fracture risk assessment. For teaching, emphasize the importance of staying updated with guidelines, identifying patient-specific risk factors, and prioritizing screenings that provide the greatest benefit. Encourage students to practice applying guidelines in varied scenarios to build confidence in clinical decision-making.

7

History & Lifestyle: 25-year-old woman at wellness visit. • Sexually active; condoms inconsistent. • Not pregnant. • No prior hepatitis C screening; no injection drug use. Family History: Noncontributory. Preventive Care Review: Up to date on Pap; wants recommended infectious disease screening based on age cohort.

Based on the vignette, which screening test is recommended for this patient?

Routine CMV serology screening

No hepatitis C screening until age 50

One-time hepatitis C antibody screening

Monthly hepatitis C RNA screening

Explanation

This question tests understanding of preventive care and screening in primary care (USMLE Step 3). Preventive care involves applying evidence-based guidelines to recommend appropriate screenings and lifestyle modifications. In this vignette, the 25-year-old woman wants age-based infectious disease screening, the recommended test is one-time hepatitis C antibody screening, aligning with USPSTF guidelines. Choice A is correct because it matches USPSTF recommendations for one-time screening in adults aged 18-79. Choice D is incorrect because it suggests no screening until age 50, ignoring the broad age range. For teaching, emphasize the importance of staying updated with guidelines, identifying patient-specific risk factors, and prioritizing screenings that provide the greatest benefit. Encourage students to practice applying guidelines in varied scenarios to build confidence in clinical decision-making.

8

History & Lifestyle: 25-year-old woman presents for wellness visit. • Sexually active with male partners; uses condoms inconsistently. • No prior HPV vaccination. • No history of abnormal Pap tests; last Pap never done. • No STI symptoms. • Drinks alcohol on weekends; no tobacco. Family History: Mother healthy; no gynecologic cancers. Preventive Care Review: Not pregnant; LMP 2 weeks ago. Interested in preventive care and vaccines. Physical exam normal.

Identify the most important vaccine that this patient needs.

HPV vaccine series initiation

RSV vaccine for older adults

Pneumococcal conjugate vaccine (PCV20)

Zoster recombinant vaccine

Explanation

This question tests understanding of preventive care and screening in primary care (USMLE Step 3). Preventive care involves applying evidence-based guidelines to recommend appropriate screenings and lifestyle modifications. In this vignette, the 25-year-old sexually active woman has no prior HPV vaccination, the most important vaccine is HPV vaccine series initiation, aligning with ACIP guidelines. Choice A is correct because it matches ACIP recommendations for HPV vaccination up to age 26 in those not previously vaccinated. Choice B is incorrect because it suggests zoster vaccine, which is recommended starting at age 50. For teaching, emphasize the importance of staying updated with guidelines, identifying patient-specific risk factors, and prioritizing screenings that provide the greatest benefit. Encourage students to practice applying guidelines in varied scenarios to build confidence in clinical decision-making.

9

History & Lifestyle: 25-year-old woman presents for preventive care. • Sexually active; no prior cervical cancer screening. • No immunocompromising conditions. • No DES exposure. • Not pregnant. Family History: Aunt with breast cancer; no cervical cancer. Preventive Care Review: Asks when she should start Pap testing and how often. Exam unremarkable.

What preventive measure is most appropriate for the patient's age group?

Cervical cytology every 3 years

Cervical cytology every year indefinitely

HPV co-testing every 5 years

No cervical screening until age 30

Explanation

This question tests understanding of preventive care and screening in primary care (USMLE Step 3). Preventive care involves applying evidence-based guidelines to recommend appropriate screenings and lifestyle modifications. In this vignette, the 25-year-old woman has no prior cervical screening, the most appropriate measure is cervical cytology every 3 years, aligning with USPSTF guidelines. Choice A is correct because it matches USPSTF recommendations for cytology every 3 years from ages 21-29. Choice D is incorrect because it suggests no screening until age 30, but screening starts at 21. For teaching, emphasize the importance of staying updated with guidelines, identifying patient-specific risk factors, and prioritizing screenings that provide the greatest benefit. Encourage students to practice applying guidelines in varied scenarios to build confidence in clinical decision-making.

10

What is the most appropriate recommendation for colorectal cancer surveillance?

Defer surveillance as long as his disease remains in clinical remission.

Annual screening with a stool-based DNA test is an acceptable alternative.

Begin screening with colonoscopy at age 45, consistent with average-risk guidelines.

Schedule a colonoscopy now with random biopsies for dysplasia.

Explanation

Patients with inflammatory bowel disease (IBD) are at increased risk for colorectal cancer and require surveillance, not average-risk screening. For patients with left-sided colitis or pancolitis, surveillance colonoscopy should begin 8-10 years after the onset of symptoms. This patient, with a 12-year history, is overdue. The procedure involves taking multiple random biopsies throughout the colon to look for dysplasia.

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