USMLE Step 1 Question of the Day
Test your knowledge with a hand-picked multiple-choice question.
A 27-year-old man with schizophrenia started risperidone 2 mg nightly 6 weeks ago. He reports fewer auditory hallucinations but now has decreased libido, erectile dysfunction, and bilateral galactorrhea. Past medical history includes obesity and prediabetes; he does not use illicit drugs. Vital signs are normal. Examination shows mild gynecomastia without rigidity or tremor. Labs: fasting glucose 122 mg/dL, LDL 148 mg/dL, prolactin 52 ng/mL, creatinine 0.9 mg/dL, and normal AST/ALT. EKG shows normal intervals. He is concerned about why this drug helps his voices. Family history is notable for type 2 diabetes. Weight has increased by 6 pounds. He denies substance use and has been adherent to medication.
This medication's therapeutic effect is mediated through which mechanism?