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Central Idea Practice Test

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Q1

Read the passage, then answer: What is the central idea of the passage?

In 1928, Alexander Fleming returns to his laboratory after a brief holiday and notices something that looks, at first glance, like a failure. A dish of bacteria has been contaminated by a stray mold, and the colonies nearest the intruder appear strangely thinned, as if an invisible boundary has been drawn. Many researchers might discard the plate, since contamination usually ruins careful work, but Fleming pauses long enough to ask why the bacteria retreat.

He tests the mold’s effect by transferring it to fresh cultures, and the same clearing appears, repeating with a consistency that suggests a chemical agent rather than mere coincidence. Fleming concludes that the mold releases a substance capable of inhibiting bacterial growth, and he names it penicillin after the mold genus, Penicillium. However, he also recognizes a practical obstacle, because the substance is unstable and difficult to purify with the tools available to him.

For years, penicillin remains more promise than medicine, not because the idea is flawed, but because the engineering is unfinished. In the early 1940s, Howard Florey and Ernst Chain, working with a larger team, develop methods to concentrate and produce penicillin in usable quantities. Their work turns Fleming’s observation into a treatment that can be tested, refined, and distributed, especially when wartime injuries make infection a widespread threat.

The story is often told as a tale of luck, yet the deeper lesson is that discovery depends on attention and persistence. An accident provides the initial clue, but careful questioning, repeated experiments, and later collaboration convert that clue into a tool that saves lives.

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