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Pathophysiology · Lessons

Pathophysiology lessons

11 sections · 96 skills · work through the full outline skill by skill — read the long-form lesson or flip through the slide-style version.
Long-form lessonsSlide-style lessons

Pathophysiology

Practice 96 skills across this outline.

Recommended next
IBD: Crohn's vs. Ulcerative Colitis
GI and Hepatobiliary Pathophysiology · Upper GI and Inflammatory Disorders
Long-form lesson
Weighting distribution
26 categories
Reproductive Pathophysiology
9%
GI and Hepatobiliary Pathophysiology · Upper GI and Inflammatory Disorders
5%
GI and Hepatobiliary Pathophysiology · Liver, Gallbladder, and Pancreas
5%
Hematology and Immune Pathophysiology · Anemia and Hemostasis
5%
Clinical Reasoning and Data Skills · Signs, Symptoms, and Laboratory Patterns
5%
Renal and Fluid Balance Pathophysiology · Acute and Chronic Kidney Disease
5%

Skills

The comprehensive taxonomy of pathophysiology — drill into a card to work its skills.

GI and Hepatobiliary Pathophysiology · Upper GI and Inflammatory Disorders

4 core skills5% total weight
0/4 completed
4 skills to mastery
1
IBD: Crohn's vs. Ulcerative ColitisRecommended
Long-form
2
MalabsorptionAvailable
Long-form
3
Peptic Ulcer DiseaseAvailable
Long-form
4
GERDAvailable
Long-form

GI and Hepatobiliary Pathophysiology · Liver, Gallbladder, and Pancreas

4 core skills5% total weight
0/4 completed
4 skills to mastery
1
Cirrhosis & Portal HypertensionAvailable
Long-form
2
HepatitisAvailable
Long-form
3
PancreatitisAvailable
Long-form
4
Jaundice MechanismsAvailable
Long-form

Hematology and Immune Pathophysiology · Infection and Sepsis

3 core skills4% total weight
0/3 completed
3 skills to mastery
1
Fever & Inflammatory MarkersAvailable
Long-form
2
Sepsis & Cytokine EffectsAvailable
Long-form
3
Innate & Adaptive ImmunityAvailable
Long-form

Hematology and Immune Pathophysiology · Anemia and Hemostasis

4 core skills5% total weight
0/4 completed
4 skills to mastery
1
Disseminated Intravascular Coagulation (DIC)Available
Long-form
2
Anemia Types by MCVAvailable
Long-form
3
Hemolysis & BilirubinAvailable
Long-form
4
Thrombosis & EmbolismAvailable
Long-form

Foundations of Pathophysiology · Fluids, Electrolytes, and Acid–Base

5 core skills3% total weight
0/5 completed
5 skills to mastery
1
Potassium DisordersAvailable
Long-form
2
Sodium DisordersAvailable
Long-form
3
Fluid Compartments & TonicityAvailable
Long-form
4
Edema MechanismsAvailable
Long-form
5
Acid-Base DisordersAvailable
Long-form

Foundations of Pathophysiology · Genetics, Immunity, and Neoplasia

4 core skills2% total weight
0/4 completed
4 skills to mastery
1
Neoplasia BasicsAvailable
Long-form
2
Genetic Contributions to DiseaseAvailable
Long-form
3
AutoimmunityAvailable
Long-form
4
Hypersensitivity Types I-IVAvailable
Long-form

Foundations of Pathophysiology · Cellular Injury and Adaptation

5 core skills3% total weight
0/5 completed
5 skills to mastery
1
Reversible vs. Irreversible InjuryAvailable
Long-form
2
Mechanisms of Cell InjuryAvailable
Long-form
3
Necrosis vs. ApoptosisAvailable
Long-form
4
Inflammation MediatorsAvailable
Long-form
5
Tissue Repair & FibrosisAvailable
Long-form

Foundations of Pathophysiology · Hemodynamics and Shock

4 core skills2% total weight
0/4 completed
4 skills to mastery
1
Organ Hypoperfusion & MODAvailable
Long-form
2
Blood Pressure, Flow & ResistanceAvailable
Long-form
3
SIRS & SepsisAvailable
Long-form
4
Types of ShockAvailable
Long-form

Clinical Reasoning and Data Skills · Case-Based Integration

3 core skills4% total weight
0/3 completed
3 skills to mastery
1
Distinguishing Similar PresentationsAvailable
Long-form
2
Multi-System IntegrationAvailable
Long-form
3
Rationale for InterventionsAvailable
Long-form

Clinical Reasoning and Data Skills · Signs, Symptoms, and Laboratory Patterns

4 core skills5% total weight
0/4 completed
4 skills to mastery
1
Vital Signs: Shock & Respiratory FailureAvailable
Long-form
2
Recognizing Red FlagsAvailable
Long-form
3
Interpreting Basic LabsAvailable
Long-form
4
Mechanism-to-Symptom MappingAvailable
Long-form

Renal and Fluid Balance Pathophysiology · Renal Disease: Electrolyte, Acid–Base Disturbances

4 core skills4% total weight
0/4 completed
4 skills to mastery
1
Fluid Overload in Renal DiseaseAvailable
Long-form
2
Hyperkalemia in Renal FailureAvailable
Long-form
3
RAAS & Volume RegulationAvailable
Long-form
4
Metabolic Acidosis in Renal FailureAvailable
Long-form

Renal and Fluid Balance Pathophysiology · Acute and Chronic Kidney Disease

4 core skills5% total weight
0/4 completed
4 skills to mastery
1
Acute Kidney Injury (AKI)Available
Long-form
2
Chronic Kidney Disease (CKD)Available
Long-form
3
Nephrotic vs. Nephritic SyndromeAvailable
Long-form
4
UremiaAvailable
Long-form

Neurologic Pathophysiology · Seizures and Neurodegeneration

3 core skills4% total weight
0/3 completed
3 skills to mastery
1
Status EpilepticusAvailable
Long-form
2
Neurodegenerative DiseasesAvailable
Long-form
3
Seizure ThresholdAvailable
Long-form

Neurologic Pathophysiology · Stroke and Intracranial Processes

3 core skills5% total weight
0/3 completed
3 skills to mastery
1
Cerebral Perfusion & IschemiaAvailable
Long-form
2
Increased ICP & HerniationAvailable
Long-form
3
Ischemic vs. Hemorrhagic StrokeAvailable
Long-form

Respiratory Pathophysiology · Obstructive and Restrictive Lung Disease

4 core skills3% total weight
0/4 completed
4 skills to mastery
1
Obstructive vs. Restrictive PatternsAvailable
Long-form
2
Asthma PathophysiologyAvailable
Long-form
3
COPD: Chronic Bronchitis vs. EmphysemaAvailable
Long-form
4
Restrictive Lung DiseaseAvailable
Long-form

Respiratory Pathophysiology · Pulmonary Vascular Disease

3 core skills3% total weight
0/3 completed
3 skills to mastery
1
Pulmonary HypertensionAvailable
Long-form
2
Pulmonary EmbolismAvailable
Long-form
3
Cor PulmonaleAvailable
Long-form

Respiratory Pathophysiology · Gas Exchange and Respiratory Failure

4 core skills3% total weight
0/4 completed
4 skills to mastery
1
ARDS (Acute Respiratory Distress Syndrome)Available
Long-form
2
V/Q Mismatch vs. ShuntAvailable
Long-form
3
Hypoxemia vs. HypercapniaAvailable
Long-form
4
Oxygen Transport & HemoglobinAvailable
Long-form

Cardiovascular Pathophysiology · Heart Failure and Valvular Disease

4 core skills3% total weight
0/4 completed
4 skills to mastery
1
Valve Stenosis vs. RegurgitationAvailable
Long-form
2
Pulmonary EdemaAvailable
Long-form
3
Systolic vs. Diastolic HFAvailable
Long-form
4
Compensatory Mechanisms in HFAvailable
Long-form

Cardiovascular Pathophysiology · Hypertension and Vascular Disease

4 core skills2% total weight
0/4 completed
4 skills to mastery
1
Atherosclerosis & Plaque RuptureAvailable
Long-form
2
Aneurysms & DissectionsAvailable
Long-form
3
Primary vs. Secondary HypertensionAvailable
Long-form
4
Peripheral Artery Disease (PAD)Available
Long-form

Cardiovascular Pathophysiology · Ischemic Heart Disease

4 core skills2% total weight
0/4 completed
4 skills to mastery
1
MI ComplicationsAvailable
Long-form
2
Stable Angina vs. ACSAvailable
Long-form
3
Cardiac BiomarkersAvailable
Long-form
4
Myocardial Infarction PathophysiologyAvailable
Long-form

Cardiovascular Pathophysiology · Arrhythmias and Conduction Disorders

3 core skills2% total weight
0/3 completed
3 skills to mastery
1
Cardiac Conduction & ArrhythmiasAvailable
Long-form
2
Tachyarrhythmia vs. BradyarrhythmiaAvailable
Long-form
3
Electrolytes & Cardiac ExcitabilityAvailable
Long-form

Endocrine and Metabolic Pathophysiology · Diabetes and Metabolic Disorders

4 core skills5% total weight
0/4 completed
4 skills to mastery
1
Hyperosmolar Hyperglycemic State (HHS)Available
Long-form
2
Hypoglycemia & CounterregulationAvailable
Long-form
3
Type 1 vs. Type 2 DiabetesAvailable
Long-form
4
Diabetic Ketoacidosis (DKA)Available
Long-form

Endocrine and Metabolic Pathophysiology · Thyroid and Adrenal Disorders

3 core skills4% total weight
0/3 completed
3 skills to mastery
1
Addison vs. Cushing SyndromeAvailable
Long-form
2
Stress Response & CortisolAvailable
Long-form
3
Hyperthyroidism vs. HypothyroidismAvailable
Long-form

Musculoskeletal and Integumentary Pathophysiology · Skin, Wounds, and Burns

3 core skills5% total weight
0/3 completed
3 skills to mastery
1
Pressure InjuriesAvailable
Long-form
2
Burn PathophysiologyAvailable
Long-form
3
Impaired Wound HealingAvailable
Long-form

Musculoskeletal and Integumentary Pathophysiology · Inflammatory and Degenerative MSK Disorders

3 core skills5% total weight
0/3 completed
3 skills to mastery
1
OsteoporosisAvailable
Long-form
2
GoutAvailable
Long-form
3
Osteoarthritis vs. Rheumatoid ArthritisAvailable
Long-form

Reproductive Pathophysiology

3 core skills9% total weight
0/3 completed
3 skills to mastery
1
Reproductive Hormone ImbalancesAvailable
Long-form
2
PreeclampsiaAvailable
Long-form
3
Physiologic Changes of PregnancyAvailable
Long-form