Cell Biology

Help Questions

NCLEX-PN › Cell Biology

Questions 1 - 10
1

Which of the following organelles is responsible for cellular respiration?

The mitochondria

The ribosomes

The peroxisomes

The centrioles

Explanation

Aerobic cellular respiration occurs exclusively in the mitochondria. These organelles are present in greater number in cells that require a large supply of ATP, such as striated muscle cells, liver cells, and sperm cells.

2

Which of the following organelles is responsible for protein synthesis?

Ribosomes

Lysosomes

The smooth endoplasmic reticulum

The nucleus

Explanation

While the nucleus houses the DNA and plays an integral role in the transcription of genetic code in order to produce specific proteins, actual protein synthesis is carried out by the ribosomes. These organelles consist of two subunits and are either independent in the cytoplasm of the cell or housed in the rough endoplasmic reticulum. Note that ribosomes can be in the cytoplasm or on the endoplasmic reticulum, hence making it rough.

3

What organelle is considered to be the "powerhouse of the cell," due to it's role in production of ATP?

Mitochondria

The Golgi apparatus

The rough endoplasmic reticulum

The nucleus

Explanation

Mitochondria are often called "the powerhouse of the cell" because they produce ATP, the body's most basic unit of energy. The nucleus houses the cell's DNA, the rough endoplasmic reticulum is the site of cellular protein manufacturing, and the Golgi apparatus packages protein manufactured in the cell for release and transport to the rest of the body.

4

Which organelle is responsible for synthesis of lipids within the cell?

The smooth endoplasmic reticulum (ER)

The Golgi apparatus

The mitochondria

The nucleus

Explanation

The majority of lipid production within the cell occurs within the smooth endoplasmic reticulum. It is also the site of production of steroids and phospholipids. The Golgi apparatus is responsible for packaging of cell products for transport outside of the cell. The mitochondria produce ATP, and the nucleus houses the DNA.

5

All of the cells of the human body except sex cells and undifferentiated stem cells are termed __________ cells.

Somatic

Gamete

Chromatic

Eukaryotic

Explanation

All of the cells of the human body except sex cells are termed somatic cells. These are diploid cells, meaning that they contain two homologous copies of each chromosome. Sex cells (eggs and sperm) are haploid cells, containing just one set of chromosomes in each cell. All human cells are eukaryotic, because they contain a nucleus and organelles within a cellular membrane.

6

The chemotherapeutic agent vinblastine interferes with the assembly of microtubules. This is effective in the treatment of certain cancers due to what cellular effect?

Disruption of the formation of mitotic spindles

Inhibition of mitochondrial function

Inhibition of DNA synthesis

Destabilization of cellular membranes

Explanation

Vinblastine and similar chemotherapeutic agents function by disrupting the formation and stability of microtubules in the cell. Because cell division is dependent on microtubule function, loss of microtubule integrity targets rapidly-reproducing cells such as cancer cells.

7

A human cell spends 90% of its lifetime in which phase of the cell cycle?

Interphase

Mitotic phase

Cytokinesis

Gap 1

Explanation

90% of the cell cycle is spent in interphase. This time is also termed the "resting phase" as it is absorbing nutrients and replicating cellular elements in preparation for cell division. This phase includes the stages Gap 1 and Gap 2. Mitosis and cytokinesis, the final stages in cell division, are both relatively short compared to interphase, accounting for approximately 10% of the cell cycle.

8

Which of the following is not a function of the cell membrane?

Synthesize proteins

Anchors the cytoskeleton to hold the shape of the cell

Attaches to the extracellular matrix and other cells to create tissues

Regulates passage of substances into and out of the cell

Explanation

The cell membrane has many purposes. It anchors the cytoskeleton to give the cell shape and structure. It houses proteins that both interact with signaling molecules from outside the cell and communicate with secondary messengers within the cell. It facilitates the absorption and release of electrolytes, water, and vesicles carrying proteins or other molecules. It forms junctions with other cells and connects the cell to the extracellular matrix.

One thing the cell membrane does not do, however, is act as a site of protein synthesis. That occurs primarily in the rough endoplasmic reticulum or on ribosomes in the cytoplasm.

9

The __________ makes up the structural framework of the cell.

Cytoskeleton

Rough endoplasmic reticulum

Cytoplasm

Nucleolus

Explanation

The framework of the cell is make up by the cytoskeleton. The cytoskeleton gives the cell both shape and structure, and allows the cell to attach to extracellular connective tissue in order to form tissue types. There are three major fibers that make up cytoskeleton - microfilaments (actin), intermediate filaments, and microtubules.

10

A solution is said to be __________ when it contains a lower solute concentration than the cell.

Hypotonic

Isotonic

Hypertonic

Non-tonic

Explanation

A hypotonic solution is one that contains solutes at a lower concentration than the cell. A cell, such as a red blood cell, will swell when exposed to a hypotonic solution as water moves into the cell to balance the osmotic gradient.

Page 1 of 2
Return to subject