NCLEX-PN › Bone Physiology
Which of the following is in the haversian canal?
Capillaries and nerves
Red bone marrow
White bone marrow
Periosteum
The haversian canal allows capillaries and nerves to pass through the cortical bone to nourish osteocytes, osteoclasts, and osteoblasts. Both the white and the red bone marrow are contained within trabecular bone, while the periosteum is a thin, highly innervated membrane on the outside of bone.
Calcium is required for all of the following except __________.
All of these require calcium
muscle contraction
nerve conduction
blood clotting
Calcium is essential for many processes of the body, including but not limited to nerve conduction, muscle contraction, blood clotting, and bone mineralization.
Which of the following is not a common site of hematopoietic bone marrow in an adult?
Tibia and fibula
Skull
Sternum
Pelvis
In adults, hematopoietic bone marrow is generally confined to the flat bones, including the sternum, the skull, the ribs, and the pelvis. Hematopoietic bone marrow also exists in the proximal end of the femur in most adults, but is not generally found in the tibia or fibula.
The length of long bones is increased via the hypertrophy and eventual apoptosis of chondrocytes which leave cavities that are then colonized by osteoprogenitor cells. This process is referred to as __________.
endochondral ossification
apoptotic ossification
osteoblast mineralization
endochondral mineralization
Long bones are lengthened during childhood and adolescence via a process referred to as endochondral ossification. In this process, chondrocytes of the growth plate hypertrophy and eventual die, leaving cavities that are then colonized by osteoprogenitor cells. These osteoprogenitor cells then differentiate into osteoblasts, which mineralize the newly forming bone. None of the other answers are actual processes in bone formation or physiology.
Which of the following is the term for the functional unit of compact bone?
Osteon
Lamellae
Haversian canal
Trabeculae
The functional unit of compact bone is the osteon. The osteon is formed by concentric layers of compact bone called lamellae. These surround a central canal called the haversian canal. Trabeculae are the functional units of cancellous (spongy) bone.
Bones are made up of which of the following three tissue types?
Cortical bone, cancellous bone, and bone marrow
Compact bone, white marrow, and red marrow
Cancellous bone, fat, and bone marrow
Cancellous bone, spongy bone, and and trabecular bone
Bones are made up of the following three primary tissue types:
I: Cortical bone, which is the hard exterior layer (also referred to as "compact bone);
II: Cancellous bone, which is the porous bone tissue that fills the center of bones (also referred to as "spongy bone" or "trabecular" bone tissue); and
III: Bone marrow, a hematopoietic tissue that fills spaces in trabecular bone.
Muscle is attached to the periosteum of bone via which of the following?
Tendons
Ligaments
Sutures
Articular cartilage
Muscle attaches to bone via tendons, fibrous extensions of the sheath of the muscle body that are primarily composed of tightly packed collagen fibers. In comparison, ligaments attach bones to other bones without involvement with a muscle, such as the ligaments between the metacarpals of the wrist. Sutures are fibrous joints of the cranium, and hyaline cartilage is at the point of articulation of many bones but it is neither incorporated into muscle structure, nor does it attach to the bone with which it articulates. Rather, articular cartilage primarily serves to allow bones to glide more easily over each other during movement.
In regards to bone marrow, "red marrow" is primarily made up of ___________ cells, while "yellow marrow" is primarily made up of ___________ cells.
hematopoietic. . . fat
erythrocytic. . . leukocytic
proliferating. . . calcified
active. . . dormant
Variation in color of bone marrow cells is not related to their level of activity, calcification, or the types of blood cells they produce. Rather, "red marrow" is primarily hematopoietic cells (both red and white progenitor cells) while "yellow marrow" is primarily composed of fat cells.
In what zone of endochondral ossification do the chondrocytes typically die off, leaving cavities for colonization by osteoprogenitor cells?
The zone of calcification
The zone of ossification
The zone of proliferation
The resting zone
The zone of maturation
The behavior of cells in the zones of endochondral ossification is as follows:
Which of the following lists the zones of endochondral ossification in the correct order?
Resting, proliferation, maturation, calcification, ossification
Proliferation, calcification, maturation, ossification, resting
Maturation, proliferation, resting, ossification, calcification
Proliferation, maturation, resting, calcification, ossification
There are five distinct zones in regions of endochondral ossification. These are the resting zone, the zone of proliferation, the zone of maturation, the zone of calcification, and the zone of ossification.