Reduction Reactions - MCAT Biological and Biochemical Foundations of Living Systems

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Question

What reagent would be best suited to accomplish the transformation shown below?

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Answer

Reduction of an ester to an alcohol requires a strong reducing agent, such as .

is not a strong enough reducing agent for this reaction. Hydrogenation and reaction with zinc would reduce the nitro group to an amino group instead of affecting the carboxylic acid. is a Grignard reagent, and would not function as a reducing agent.

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