Krebs Cycle - MCAT Biological and Biochemical Foundations of Living Systems

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Question

Within the Krebs cycle, L-malate and NAD+ come together to form oxaloacetate, NADH, and H+. What type of chemical reaction is responsible for this step in the cycle?

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Answer

In order for oxaloacetate to be formed, malate must lose electrons, which is the definition of an oxidation reaction. Alternately, NAD+ is reduced (gains electrons) to form NADH and H+.

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