Immune System

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Biology › Immune System

Questions 1 - 10
1

Which type of cell is part of adaptive immunity?

T-cell lymphocytes

Neutrophils

Monocytes

Macrophages

Explanation

Adaptive immunity involves immune cells created due to previously experiencing an infection by a particular pathogen. T-cell lymphocytes mature in the thymus, and recognize a specific antigen. T-cells and B-cells work to produce antibodies against a specific antigen, making them highly specific. This specification is only found in the adaptive immune system

In contrast, the innate immune system can respond to any pathogen, regardless of previous exposure, Neutrophils, monocytes, and macrophages are all part of the innate immune response and help with phagocytosis and inflammation.

2

Which type of cell is part of adaptive immunity?

T-cell lymphocytes

Neutrophils

Monocytes

Macrophages

Explanation

Adaptive immunity involves immune cells created due to previously experiencing an infection by a particular pathogen. T-cell lymphocytes mature in the thymus, and recognize a specific antigen. T-cells and B-cells work to produce antibodies against a specific antigen, making them highly specific. This specification is only found in the adaptive immune system

In contrast, the innate immune system can respond to any pathogen, regardless of previous exposure, Neutrophils, monocytes, and macrophages are all part of the innate immune response and help with phagocytosis and inflammation.

3

What cell is responsible for releasing free antibodies into the bloodstream?

Plasma cells

T-lymphocytes

Neutrophils

B-lymphocytes

Explanation

Each B-lymphocyte cell is responsible for creating one specific antibody. If the B-lymphocyte's antibody matches to the right antigen, the lymphocyte will differentiate into a plasma cell. Plasma cells release free antibodies into the bloodstream. The transition process from B-cell to plasma cell is mediated by helper T-cells.

4

What cell is responsible for releasing free antibodies into the bloodstream?

Plasma cells

T-lymphocytes

Neutrophils

B-lymphocytes

Explanation

Each B-lymphocyte cell is responsible for creating one specific antibody. If the B-lymphocyte's antibody matches to the right antigen, the lymphocyte will differentiate into a plasma cell. Plasma cells release free antibodies into the bloodstream. The transition process from B-cell to plasma cell is mediated by helper T-cells.

5

Which of the following is NOT an aspect of the innate immune system?

Antibodies in the blood

Stomach acid

Skin

Mucous

Enzymes in sweat, tears, and saliva that kill bacteria

Explanation

The innate immune system is a general defense against infections. Antibodies are very specific to the type of infection they can fight. Thus antibodies are considered specific defense.

6

How is VDJ recombination indispensible for adaptive immunity?

It allows for the generation of diverse and variable antibodies that are able to recognize a myraid of antigens

It allows for the generation of diverse antigens to recognize many antibodies

VDJ recombination is not involved in adaptive immunity

It promotes clotting and macrophage recruitment to wounds

It prevents integration of viral DNA into host DNA

Explanation

VDJ recombination occurs during early B- and T-cell maturation, resulting in diverse antibodies and T-cells. This DNA recombination occurs between the V, D, and J segments of the antibody or T-cell before transcription occurs. As a result, a unique sequence is generated, transcribed, and then translated to a functional protein. This recombination is responsible for creating the unique series of antibodies that the body is capable of producing in order to detect the various antigens represented by foreign pathogens.

7

The human immune system includes several types of specialized cells whose role is to eliminate invaders threatening the health of the body.

A certain immune cell has a certain type of antibody on its surface. When it comes in contact with a pathogen (attacker) that matches its antibodies, the immune cell signals other immune cells to attack the invader and produces more antibodies in order to flag other invaders of the same type. What type of cell is this immune cell?

B-lymphocyte

Helper T-cell

Killer T-cell

Natural killer cell

Macrophage

Explanation

B-lymphocytes are the immune system's "memory"—once the body is attacked by a certain virus or bacteria, the body produces B-lymphocytes that can specifically recognize that disease. When the B-lymphocyte comes in contact with the disease (recognized by antibodies) it signals killer T-cells and helper T-cells to attack, and creates more antibodies to signal additional T-cells.

Natural killer cells destroy any cells of the human body that have become infected by an attacker.

Macrophages are a general clean-up cell that sweep up debris, old cells, and sometimes attackers via phagocytosis.

Killer and helper T-cells are both activated by B-lymphocytes

8

How is VDJ recombination indispensible for adaptive immunity?

It allows for the generation of diverse and variable antibodies that are able to recognize a myraid of antigens

It allows for the generation of diverse antigens to recognize many antibodies

VDJ recombination is not involved in adaptive immunity

It promotes clotting and macrophage recruitment to wounds

It prevents integration of viral DNA into host DNA

Explanation

VDJ recombination occurs during early B- and T-cell maturation, resulting in diverse antibodies and T-cells. This DNA recombination occurs between the V, D, and J segments of the antibody or T-cell before transcription occurs. As a result, a unique sequence is generated, transcribed, and then translated to a functional protein. This recombination is responsible for creating the unique series of antibodies that the body is capable of producing in order to detect the various antigens represented by foreign pathogens.

9

The human immune system includes several types of specialized cells whose role is to eliminate invaders threatening the health of the body.

A certain immune cell has a certain type of antibody on its surface. When it comes in contact with a pathogen (attacker) that matches its antibodies, the immune cell signals other immune cells to attack the invader and produces more antibodies in order to flag other invaders of the same type. What type of cell is this immune cell?

B-lymphocyte

Helper T-cell

Killer T-cell

Natural killer cell

Macrophage

Explanation

B-lymphocytes are the immune system's "memory"—once the body is attacked by a certain virus or bacteria, the body produces B-lymphocytes that can specifically recognize that disease. When the B-lymphocyte comes in contact with the disease (recognized by antibodies) it signals killer T-cells and helper T-cells to attack, and creates more antibodies to signal additional T-cells.

Natural killer cells destroy any cells of the human body that have become infected by an attacker.

Macrophages are a general clean-up cell that sweep up debris, old cells, and sometimes attackers via phagocytosis.

Killer and helper T-cells are both activated by B-lymphocytes

10

Which of the following is NOT an aspect of the innate immune system?

Antibodies in the blood

Stomach acid

Skin

Mucous

Enzymes in sweat, tears, and saliva that kill bacteria

Explanation

The innate immune system is a general defense against infections. Antibodies are very specific to the type of infection they can fight. Thus antibodies are considered specific defense.

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