Understanding Spermatogenesis - Biology

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Question

What is the primary role of androgen-binding protein (ABP) in the process of spermatogenesis?

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Answer

A very high level of testosterone (15-70 times greater than in the blood) is required for the initiation and maintenance of spermatogenesis, and androgen-binding protein's most direct role is ensuring this high concentration of testosterone by preventing absorption of testosterone back into the body across the blood-testis barrier.

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