Biochemistry › Protein Catabolism Regulation
Which enzyme catalyzes the rate-limiting step of the urea cycle?
Carbamoyl phosphate synthetase
Carbamoyl phosphate dehydrogenase
Argininosuccinate lyase
Ornithine transcarbamylase
Carbamoyl phosphate synthetase is the rate-limiting step of the urea cycle. It is the first step of the urea cycle and occurs exclusive in the mitochondria of hepatic and renal cells.