Protein Catabolism Intermediates

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Biochemistry › Protein Catabolism Intermediates

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1

Phenylketonuria is a genetic disorder resulting in a lack of phenylalanine hydroxylase activity. During the first step of phenylalanine metabolism, phenylalanine is hydroxylated into what amino acid?

Tyrosine

Tryptophan

Serine

Threonine

Alanine

Explanation

The first step in phenylalanine metabolism is conversion of phenylalanine to tyrosine. Tyrsoine is simply a hydroxylated version of phenylalanine.

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