Biochemistry › Lipids
Which of the following can be used to describe fatty acids?
Amphipathic
Amphoteric
Hydrophilic
Hydrophobic
Inorganic
Fatty acids are composed of a carboxylic acid head and a long carbon chain. The carbon chain is non-polar, while the carboxylic acid head is polar. A molecule with both a polar and non-polar parts is known as amphipathic. The word amphoteric means a molecule that can act as either an acid or a base. Finally, just as a fatty acid has both polar and non-polar ends, those same ends are also hydrophilic and hydrophobic, respectively.
Saponification involves cleavage of what type of bond?
Ester bond
Peptide bond
Anhydride bond
Glycosidic bond
Saponification is the general term for a chemical reaction between an acid and a base to form a salt. This process can be used to make soap (the salt) if one mixes an oil or fat (the acid) with lye (the base). Triglycerides (triesters) are the main materials that are saponified. We can saponify triglycerides by treating them with a strong base (such as lye), which accelerates cleavage of the ester bond to release the fatty acid and glycerol. Soap can then be precipitated by a salting out process.
Which is not a characteristic of an unsaturated fatty acid?
An amino group
A bent or "kinked" structure
One or more double bonds
A smaller number of hydrogens than a saturated fat acid of the same length
A lower boiling point than a saturated fatty acid of the same length.
The key to this question is realizing that unsaturated fatty acids contain one or more double bonds, while saturated fatty acids contain no double bonds. From that information, you can make inferences about most of the other answer choices. Because of the double bonds within an unsaturated fatty acid, there are fewer hydrogens attached to the carbon molecules. Additionally, the double bonds result in a bent/kinked structure. Furthermore, this bent/kinked structure results in a lower boiling point. This structure disrupts packing, and reduces the van der Waals interactions, thus reducing the boiling point. Finally, fatty acids do not contain amino groups, so this is the correct answer.
Which of these are not found in cell membranes?
Triacylglycerols
Phosphoacylglycerols
Cholesterol
Glycolipids
Phosphoacylglycerols, glycolipids, and cholesterol are all part of cell membranes. Phosphoacylglycerols and glycolipids are major components of cell membranes. Glycolipids mainly have a communicative role in which they act as markers for cell recognition. They also provide stability for the cell and help form tissues. Cholesterol helps maintain the fluidity of cell membranes, along with securing important proteins in the membrane.
Triacylglycerols, however, are not found in cell membranes. These are triesters formed by esterification of three fatty acids to glycerol. Oils are triacylglycerols that are liquids at room temperature, while fats are triacylglycerols that are solids at room temperature. Triacylglycerols are stored forms of energy for living systems.
Which group is not present in a phosphatidic acid?
Choline
Glycerol
Fatty acids
Phosphate
Phosphatidic acids consist of all of the structures listed, except for choline. Choline is a nitrogen-containing salt with an alcohol group. It is a precursor to the neurotransmitter acetylcholine and some classes of phospholipids including sphingomyelin and phosphatidylcholine.
What is the name of the molecule shown above?
Phosphatidylserine
Phosphaditic acid
Phosphatidylethanolamine
Phosphatidylcholine
Triglyceride
A triglyceride has three fatty acids; this molecule has two (represented by the R chains). Phosphaditic acid is the simplest of the diacyl-glycerophospholipids; its phosphate group is bonded to only to the glycerol, and nothing else, which is not the case here. Among the three other choices, all of them accurately describe this molecule as a diacylglyceride phospholipid (hence the prefix phosphatidyl-); the phosphate is attached to serine as a head group, not a choline, nor ethanolamine,
.
Which of the following is not a correct function of cholesterol?
Helps maintain rigidity of blood vessels
A component of animal cell membranes
A precursor to steroid hormones, such as vitamin D
A precursor to bile salts
All of these are normal functions of cholesterol
To answer this question, let's go through each of the answer choices to see what cholesterol's functions are.
It turns out that cholesterol is an important component of animal cell membranes. It helps to maintain both the structural integrity of the membrane, as well as its fluidity.
Cholesterol also serves as a precursor for all steroid hormones. In fact, if you look through all the steroid hormones, you'll find that they all have the characteristic 4-ring structure that cholesterol has.
Cholesterol also functions as a precursor for the production of bile salts in the liver. These bile salts are subsequently stored in the gallbladder and, when needed, released into the duodenum of the small intestine to aid in the digestion of lipids.
Cholesterol can deposit into the inner lining of blood vessels, however this is not a normal function of cholesterol. Rather, this is a pathological process that leads to a condition called atherosclerosis. This, in turn, can lead to the hardening of blood vessels, as well as contribute to the formation of blood clots that can impede the flow of blood in that vessel. These clots can also become dislodged and travel throughout the circulatory system, where it can become trapped in other blood vessels. This is a dangerous situation, because it can potentially lead to heart attack or stroke.
Which of these statements is false?
Unsaturated fatty acids cause higher levels of LDL than saturated fatty acids.
Plant oils contain extremely low quantities of cholesterol.
Plant oils are healthier because they generally contain more unsaturated fats than found in animal fats.
Heart disease is associated with diets high in saturated fatty acids.
Saturated fats decrease the ratio of HDL to LDL in the blood.
Unsaturated fatty acids lead to lower LDL levels ("bad cholesterol") than saturated fatty acids. Thus, unsaturated fatty acids are healthier than saturated fatty acids. Plant oils do contain more unsaturated fatty acids than saturated fatty acids, so they are much healthier than animal fats - also note that cholesterol is largely an animal-derived lipid and is almost exclusively found in animal fats (however some research shows that very low levels of cholesterol may be found in some plant products). Saturated fatty acids also lead to higher LDL levels ("bad cholesterol"), which accelerate heart disease.
The electric potential gradient of an ion across a plasma membrane __________.
increases with temperature
decreases with temperature
increases as the ion's charge increases
is independent of the concentration gradient
is around in an animal cell at rest
For animal cells at rest, the potential difference across plasma membranes is usually somewhere between and
. It is given by the Nernst equation:
Where and
are constant,
is the ion's charge,
and
are the outside and inside concentrations respectively, and
is the temperature. Therefore, the potential difference decreases as the ion's charge increases, and is not independent of the concentration gradient. It increases -- it does not decrease -- with temperature.
Why are lipids insoluble in water?
Lipids are nonpolar, while water is polar.
Lipids are polar, while water is nonpolar.
All lipids dissolve completely in water.
All lipids dissolve at least somewhat in water.
Lipids are nonpolar substances, meaning that they are hydrophobic ("water-fearing"). Water, meanwhile, is polar. A common statement to remember in biochemistry is "like dissolves like." This means that polar substances will dissolve other polar substances, while nonpolar substances will dissolve other nonpolar substances. Polar and nonpolar substances do not mix; thus, lipids and water cannot mix.