Isomerases

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Biochemistry › Isomerases

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Phosphoglucomutase is an enzyme seen in glycogen breakdown. It is responsible for converting glucose-1-phosphate ( $C_{6}H_{13}O_{9}P$ ) to glucose-6-phosphate ( $C_{6}H_{13}O_{9}P$ ).

Based on this action, to which enzyme class does phosphoglucomutase belong?

Isomerase

Lyase

Ligase

Oxidoreductase

Explanation

Phosphoglucomutase is responsible for altering the position of the phosphate on the glucose from the "1" position to the "6" position. However, notice how the molecular formula for the product and the substrate are the same. Enzymes that rearrange the structure of a molecule in this manner are referred to as isomerase enzymes.

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