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Coupled Reactions Practice Test

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Q1

Two reactions are coupled in a metabolic sequence by sharing intermediate $M$ (Reaction 1 produces $M$, Reaction 2 consumes $M$). Reaction 1 is spontaneous: $L \rightarrow M$, $\Delta G = -40\ \text{kJ/mol}$. Reaction 2 is nonspontaneous: $M \rightarrow N$, $\Delta G = +12\ \text{kJ/mol}$. When coupled as $L \rightarrow N$, which condition allows the nonspontaneous reaction to proceed thermodynamically?

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