All questions
Question 1
A 9-month-old boy is brought to the clinic for a well-child visit. His mother is concerned because he is not yet crawling. His birth history was unremarkable, and he has been meeting other milestones appropriately. On examination, he can sit unsupported, babbles, and has a pincer grasp. When placed on his stomach, he pushes up on his hands and knees and rocks back and forth. His growth parameters are at the 50th percentile for age.
Which of the following is the most appropriate next step in the management of this patient?
- Reassurance and anticipatory guidance (correct answer)
- Referral for physical therapy evaluation
- MRI of the brain and spine
- Serum creatine kinase level
Explanation: The patient is demonstrating age-appropriate developmental milestones. At 9 months, an infant should be able to sit unsupported, babble, and develop a pincer grasp, all of which this child is doing. Crawling is a variable milestone, with a wide range of normal onset; some healthy infants skip crawling altogether. The finding of rocking on hands and knees is a pre-crawling behavior, indicating that gross motor development is progressing normally. Therefore, the most appropriate next step is to reassure the mother and provide anticipatory guidance about the normal variability in achieving this milestone.
Question 2
A healthy 4-month-old infant is brought for a well-child visit. He was born full-term and has had no medical problems. He is exclusively breastfed. His immunizations are up-to-date. The mother asks which vaccines her child will receive today.
In addition to the second dose of the DTaP, Hib, and pneumococcal conjugate vaccines, which of the following immunizations is routinely recommended at this visit?
- Measles, mumps, and rubella (MMR)
- Varicella
- Inactivated poliovirus (IPV) (correct answer)
- Hepatitis A
Explanation: The standard pediatric immunization schedule in the United States includes the second doses of several vaccines at the 4-month well-child visit. These include Diphtheria, tetanus, and acellular pertussis (DTaP); Haemophilus influenzae type b (Hib); Pneumococcal conjugate (PCV13); and Inactivated poliovirus (IPV). The rotavirus vaccine is also typically given. MMR, Varicella, and Hepatitis A vaccines are all first given at or after 12 months of age.
Question 3
A 5-year-old child is brought to the clinic for a kindergarten physical. His immunization record shows he received three doses of DTaP, three doses of IPV, one dose of MMR, and one dose of varicella. He completed the Hib and PCV13 series as an infant. His last vaccinations were at age 15 months.
Which of the following sets of vaccines is most appropriate to administer at this visit?
- DTaP, IPV, MMR, and Varicella (correct answer)
- Tdap, IPV, and MMR
- DTaP and IPV only
- MMR and Varicella only
Explanation: According to the CDC immunization schedule, children should receive booster doses of certain vaccines between 4 and 6 years of age before starting school. This child is due for his fifth dose of DTaP, fourth dose of IPV, second dose of MMR, and second dose of varicella. He has only received one dose of MMR and varicella previously (typically given at 12-15 months), and the second doses are recommended at this age. He also needs boosters for DTaP and IPV. Tdap is not used for the primary series or boosters in children under age 7.
Question 4
A 6-month-old infant is brought for a well-child check. The physician is discussing injury prevention with the parents. The parents mention they recently bought a new car and want to ensure their child is safe.
Which of the following is the most appropriate car seat recommendation for this infant?
- Forward-facing car seat in the back seat
- Rear-facing car seat in the back seat (correct answer)
- Booster seat with a seatbelt in the back seat
- Rear-facing car seat in the front passenger seat with the airbag disabled
Explanation: The American Academy of Pediatrics (AAP) recommends that all infants and toddlers ride in a rear-facing car seat for as long as possible, until they reach the highest weight or height allowed by their car seat's manufacturer. This provides the best protection for the head, neck, and spine in the event of a crash. A 6-month-old infant must be in a rear-facing car seat. All children under age 13 should ride in the back seat. Placing a rear-facing seat in the front is extremely dangerous due to the risk of injury from the passenger-side airbag.
Question 5
During a well-child visit for a 4-week-old female infant, physical examination reveals a left-sided 'clunk' when the hip is adducted and posteriorly directed pressure is applied. When the hip is then abducted, another 'clunk' is felt as the femoral head relocates. The remainder of the examination is normal.
Which of the following is the most appropriate next step in management?
- Triple diapering and follow-up in 2 weeks
- Referral to an orthopedic surgeon (correct answer)
- X-ray of the hips
- Reassurance, as this is a common finding
Explanation: The physical examination findings describe a positive Barlow maneuver (dislocation of the hip with adduction) and a positive Ortolani maneuver (relocation of the dislocated hip with abduction). These findings are indicative of developmental dysplasia of the hip (DDH). A positive Ortolani or Barlow sign in an infant older than 2 weeks is a definitive indication for referral to an orthopedic surgeon for further evaluation and management, typically with a Pavlik harness. X-rays are not the preferred imaging modality in infants under 4-6 months because the femoral heads are cartilaginous; ultrasound is used instead. However, given the positive physical findings, direct referral is the most appropriate step. Triple diapering is ineffective and not recommended.
Question 6
A 12-month-old infant receives his first measles, mumps, and rubella (MMR) vaccine during a routine well-child visit. The parents call the clinic 10 days later, concerned that the child has developed a temperature of 38.9°C (102°F) and a faint, maculopapular rash on his trunk.
Which of the following is the most appropriate advice for the parents?
- Bring the child to the emergency department immediately
- This is a normal reaction; manage with antipyretics and reassurance (correct answer)
- Administer a dose of aspirin to reduce the fever
- The child should not receive any further doses of the MMR vaccine
Explanation: The MMR vaccine is a live attenuated vaccine. A common and expected reaction, occurring 7-12 days after administration, is a fever and/or a mild rash. This represents a mild, non-contagious form of the measles infection as the body mounts an immune response. This reaction is self-limited and can be managed symptomatically with antipyretics (acetaminophen or ibuprofen). It is not an allergic reaction or a contraindication to future doses. Aspirin should be avoided in children due to the risk of Reye syndrome. Emergency department evaluation is not necessary for this expected vaccine reaction in an otherwise well-appearing child.
Question 7
A 15-month-old girl is brought for a well-child visit. Her parents report that she is not yet walking independently, although she cruises along furniture and pulls to a stand easily. She says 3-4 words, babbles, and uses a pincer grasp to pick up small objects. Her physical exam is normal with no neurologic deficits.
What is the most appropriate next step in the management of this child?
- Referral for physical therapy
- X-ray of the lower extremities
- Reassurance that this is within the normal range of development (correct answer)
- Blood work including creatine kinase and thyroid studies
Explanation: The normal range for walking independently is broad, typically between 9 and 16 months. A child is not considered to have a significant gross motor delay until they are not walking by 18 months. This child is demonstrating appropriate prerequisite skills for walking, such as pulling to a stand and cruising. Her other developmental domains (language, fine motor) are also on track. Therefore, the most appropriate course of action is to reassure the parents that her development is within the normal range and to continue monitoring at subsequent well-child visits.
Question 8
A 6-month-old infant is noted to have a head circumference that has crossed from the 50th to the 98th percentile over the past 4 months. The infant's length and weight are tracking along the 50th percentile. On examination, the anterior fontanelle is full and tense, and there is splitting of the sutures. The infant has been more irritable and feeding poorly for the past week.
Which of the following is the most appropriate next step in the diagnostic workup?
- Cranial ultrasound (correct answer)
- Genetic testing for Sotos syndrome
- Endocrine evaluation for hormonal abnormalities
- Reassurance and follow-up in 1 month
Explanation: The rapid increase in head circumference crossing two major percentile lines, along with signs of increased intracranial pressure (tense fontanelle, split sutures, irritability), is highly concerning for hydrocephalus. In an infant with an open anterior fontanelle, a cranial ultrasound is the initial imaging modality of choice. It is non-invasive, does not require sedation, and can effectively visualize the ventricles to assess for dilation. MRI would be the next step if the ultrasound is abnormal or inconclusive. Reassurance is inappropriate given the red flags. While some genetic syndromes cause macrocephaly, the acute signs of increased pressure must be evaluated first.
Question 9
A 12-month-old child living in a house built in 1960 is brought in for a routine well-child visit. The child is asymptomatic and meeting all developmental milestones. Growth parameters are at the 50th percentile. The physician performs routine screening tests.
In addition to a hemoglobin/hematocrit level, which of the following screening tests is most indicated for this child?
- Serum lead level (correct answer)
- Fasting lipid panel
- Tuberculin skin test
- Urinalysis
Explanation: Universal screening for lead exposure is recommended at 12 and 24 months of age for children enrolled in Medicaid or living in areas with a high prevalence of older housing. Even for other children, risk assessment is crucial. Living in a house built before 1978 (especially before 1960) is a major risk factor for lead exposure from paint chips and dust. Therefore, a serum lead level is indicated. A fasting lipid panel is not routinely recommended until ages 9-11. Tuberculin skin testing is only for children with specific risk factors. Urinalysis is not a routine screening test at this age in an asymptomatic child.
Question 10
A 3-month-old infant is brought to the clinic by her parents, who are seeking guidance on safe sleep. They mention that their baby seems to sleep better on her stomach and often rolls over.
Which of the following is the most important component of safe sleep counseling to reduce the risk of Sudden Infant Death Syndrome (SIDS)?
- Place the infant on her back to sleep on a firm surface (correct answer)
- Use a soft mattress and bumper pads for comfort
- Co-sleep with the infant in the parents' bed for close monitoring
- Allow stomach sleeping once the infant can roll over independently
Explanation: The single most effective action to reduce the risk of SIDS is to place infants on their back ('supine') for every sleep, for naps and at night. This should be done on a firm, flat sleep surface without any soft bedding, pillows, or bumper pads. While infants who can roll from back to stomach and stomach to back independently can be allowed to remain in the sleep position they assume, parents should continue to place them on their back initially. Co-sleeping in the same bed is a risk factor for SIDS and suffocation and is discouraged. Room-sharing (infant in a separate bassinet or crib in the parents' room) is recommended.
Question 11
A 7-month-old infant is brought to the clinic. His parents report that his weight gain has been poor for the past 2 months. He was previously tracking along the 25th percentile for weight, but is now below the 3rd percentile. His length and head circumference remain at the 25th percentile. The mother is breastfeeding and has recently started introducing solid foods. The infant has 4-5 loose, non-bloody stools per day. A detailed dietary history reveals that the mother recently switched to a strict vegan diet for herself and has been making her own infant food from pureed fruits and vegetables.
This infant's failure to thrive is most likely due to which of the following?
- Inadequate caloric intake (correct answer)
- Malabsorption due to celiac disease
- Congenital heart disease
- Chronic renal insufficiency
Explanation: This infant presents with failure to thrive, specifically affecting weight ('wasting') while length and head circumference are preserved. This pattern is classic for caloric insufficiency. The history points to several potential reasons for inadequate calories: the infant may not be getting enough calories from breast milk if the mother's diet is deficient, and the homemade pureed fruits and vegetables may be low in caloric and fat density compared to iron-fortified cereals and commercial baby foods. Other causes like celiac disease, heart disease, or renal disease are less likely given the preserved linear growth and lack of other specific symptoms.
Question 12
An 18-month-old boy is brought for a routine check-up. The parents are concerned about his development. They note he does not point at objects to show interest, rarely makes eye contact, and does not respond to his name consistently. He has not started using any single words. He enjoys stacking blocks by himself but does not engage in pretend play, such as feeding a doll. His physical examination and growth are normal.
These findings are most concerning for which of the following conditions?
- Global developmental delay
- Isolated language disorder
- Hearing impairment
- Autism spectrum disorder (correct answer)
Explanation: The patient's presentation includes several red flags for autism spectrum disorder (ASD). These include impaired social communication and interaction (poor eye contact, not responding to name, lack of pointing for joint attention) and restricted, repetitive patterns of behavior or interests (lack of pretend play). While he does have a language delay, the social communication deficits are the most prominent and specific features pointing towards ASD. Hearing impairment should be ruled out, but it would not explain the lack of pointing or pretend play. Global developmental delay involves delays in at least two developmental domains, but this child's presentation is most characteristic of ASD.
Question 13
A 4-year-old boy has been refusing to put weight on his right leg for the past day. His mother reports he had a mild upper respiratory infection last week. On examination, he is afebrile. His right hip is held in a flexed, abducted, and externally rotated position. He has pain with passive internal rotation of the hip. Laboratory studies show a normal white blood cell count and erythrocyte sedimentation rate.
This patient's presentation is most consistent with transient synovitis. Which of the following is the most appropriate counseling to provide to the family?
- The child should receive prophylactic antibiotics for one year
- He will require lifelong monitoring for autoimmune disease
- This condition is self-limited and typically resolves within 1-2 weeks (correct answer)
- He should be permanently restricted from contact sports
Explanation: Transient synovitis is the most common cause of hip pain in children aged 3-10. It is a benign, self-limited inflammatory condition that typically follows a viral illness and resolves within 1-2 weeks with supportive care (rest, NSAIDs). Parents should be counseled that this condition has no long-term consequences and does not require prolonged antibiotics, ongoing monitoring, or activity restrictions once resolved. Accurate counseling helps reduce parental anxiety and prevents unnecessary interventions.
Question 14
A 12-month-old boy is in the office for his well-child visit. His mother asks for advice on nutrition. He is currently drinking 30 ounces of iron-fortified formula per day and has started eating some solid foods. His weight is at the 60th percentile, and his length is at the 55th percentile. Hemoglobin level checked via fingerstick is 11.5 g/dL.
Which of the following is the most appropriate nutritional counseling for this child's parents?
- Continue iron-fortified formula and solids until age 2
- Transition to 2% milk and limit to 16 ounces per day
- Transition to whole milk and limit to 16-24 ounces per day (correct answer)
- Transition to skim milk and encourage a variety of solids
Explanation: At 12 months of age, infants should transition from formula or breast milk to whole cow's milk. Whole milk is recommended until age 2 to provide adequate fat for brain development. Milk intake should be limited to 16-24 ounces per day to ensure the child does not fill up on milk and has an appetite for a variety of solid foods, which are crucial for obtaining iron and other nutrients. Excessive milk intake is a common cause of iron deficiency anemia in toddlers. 2% or skim milk is not recommended for children under 2 years. Continuing formula is unnecessary for a healthy, growing 1-year-old.
Question 15
During a newborn examination, a full-term male infant is noted to have a persistent Moro reflex. When a loud noise is made, he abducts and extends his arms, then adducts them. However, his right arm shows significantly less movement than his left.
This finding, considered a developmental red flag, should prompt further evaluation for which of the following?
- Cerebral palsy
- Brachial plexus injury (correct answer)
- Spinal muscular atrophy
- Congenital hypothyroidism
Explanation: An asymmetric Moro reflex is a classic red flag that points to a focal neurologic or musculoskeletal problem on the side with decreased movement. The most common cause of an asymmetric Moro reflex in a newborn is a brachial plexus injury (e.g., Erb's palsy) sustained during delivery. Other possibilities include a fractured clavicle or humerus. Cerebral palsy is typically not diagnosed in the newborn period and often presents with abnormalities of tone. Spinal muscular atrophy would cause symmetric weakness. Congenital hypothyroidism presents with poor feeding, hypotonia, and prolonged jaundice.
Question 16
A 2-month-old infant is scheduled for a well-child visit. His 4-year-old sister was diagnosed with acute lymphoblastic leukemia one week ago and is currently receiving intensive chemotherapy.
Which of the following vaccines should be avoided in the infant at this visit?
- Diphtheria, tetanus, acellular pertussis (DTaP)
- Pneumococcal conjugate (PCV13)
- Inactivated poliovirus (IPV)
- Rotavirus (correct answer)
Explanation: The rotavirus vaccine is a live attenuated oral vaccine. The virus can be shed in the stool of the vaccinated infant for up to two weeks. This poses a theoretical risk of transmission to severely immunocompromised household contacts, such as the sibling receiving chemotherapy. Therefore, the live rotavirus vaccine should be withheld. All other recommended vaccines for a 2-month-old (DTaP, Hib, PCV13, IPV) are inactivated and can be safely administered to infants living with immunocompromised individuals.
Question 17
A 2-year-old girl is brought for her well-child check. Her parents report that she says only about 15 words and does not combine words into two-word phrases. She is able to follow simple commands, points to pictures in a book when named, and her gross motor skills are appropriate for her age. She was born full-term with no complications. She has had three episodes of otitis media in the past year, all treated successfully with amoxicillin.
Which of the following is the most appropriate next step to evaluate this child's speech delay?
- Formal audiology evaluation (correct answer)
- Referral for developmental-behavioral pediatrics
- Magnetic resonance imaging of the brain
- Observation with follow-up in 6 months
Explanation: This patient presents with an expressive language delay. By age 2, a child should typically have a vocabulary of at least 50 words and be using two-word phrases. A crucial first step in the evaluation of any speech or language delay is to rule out hearing impairment. The child's history of recurrent otitis media further increases the suspicion for a conductive hearing loss due to middle ear effusion. A formal audiology evaluation is the definitive test to assess hearing ability. The other options are less appropriate as the initial step.
Question 18
A 4-year-old boy is brought for a well-child visit. His parents are concerned that he is shorter than all of his peers. His height has consistently tracked along the 5th percentile since birth, and his weight is at the 10th percentile. His growth velocity is 5.5 cm/year. Both parents are of average height. The physical examination is unremarkable, and he is meeting all developmental milestones.
Which of the following is the most likely explanation for this child's short stature?
- Growth hormone deficiency
- Constitutional growth delay
- Familial short stature (correct answer)
- Hypothyroidism
Explanation: This child's growth pattern is most consistent with familial short stature. Key features include a low-normal height percentile that is maintained consistently over time and a normal growth velocity (typically >4-5 cm/year for a preschooler). Although his parents are of 'average' height, their genetic potential may still place the child on a lower percentile. Growth hormone deficiency and hypothyroidism would typically present with a slowing of growth velocity and falling off the growth curve. Constitutional growth delay is characterized by a similar pattern but is often associated with delayed bone age and a later pubertal growth spurt, which cannot be determined yet in a 4-year-old, but familial short stature is more likely given he has been on this curve since birth.
Question 19
A 10-year-old boy is seen for a well-child checkup. His family has no significant medical history. His BMI is at the 60th percentile. He is active in sports. As part of routine preventive care, the physician considers ordering screening labs.
According to current guidelines, which of the following is the most appropriate screening to perform for this child?
- Hemoglobin A1c for diabetes
- Non-fasting lipid panel for dyslipidemia (correct answer)
- Serum lead level for lead toxicity
- Thyroid-stimulating hormone for hypothyroidism
Explanation: The American Academy of Pediatrics (AAP) and the National Heart, Lung, and Blood Institute (NHLBI) recommend universal lipid screening for all children between the ages of 9 and 11. This is done to detect familial hypercholesterolemia and other lipid disorders early. A non-fasting panel is acceptable for initial universal screening. Screening for diabetes, lead toxicity, or hypothyroidism is not universally recommended at this age for an asymptomatic child without specific risk factors.
Question 20
A 6-year-old girl is brought for a well-child exam. Her parents ask about the human papillomavirus (HPV) vaccine. They have heard it is important for preventing cancer but are unsure about the timing.
What is the most appropriate recommendation regarding HPV vaccination for this child?
- She should receive the first dose now, as it can be given starting at age 6.
- She should wait until age 11-12 to begin the vaccine series. (correct answer)
- The vaccine is only recommended for sexually active adolescents.
- She should receive it only if she has specific risk factors for HPV infection.
Explanation: The Advisory Committee on Immunization Practices (ACIP) routinely recommends HPV vaccination for all adolescents at age 11 or 12 years, although the series can be started as early as age 9. The goal is to complete the series before the onset of sexual activity, as the vaccine is most effective when given before any exposure to HPV. While it can be given at age 9, the routine recommendation is to start at age 11-12. It is a universal vaccine, not based on risk factors or sexual activity.