MCAT Biology › Pituitary and Hypothalamus
Which hormone is secreted from the anterior pituitary?
Follicle-stimulating hormone
Somatostatin
Oxytocin
Vasopressin
The pituitary gland is comprised for the anterior and posterior pituitary. The anterior pituitary arises from the oral ectoderm, while the posterior pituitary arises from the neuroectoderm. Hormones are secreted from the anterior pituitary in response to stress or to promote milk production, growth, or reproduction. Follicle-stimulating hormone (FSH) is required for growth of the reproductive system.
The posterior pituitary is responsible for production and secretion of neurohypophysical hormones, including oxytocin and vasopressin. Somatostatin is produced from within the digestive system, and signals to the anterior pituitary to inhibit growth hormone secretion.
The hormones of the anterior pituitary can be remembered by using the pneumonic "FLAT PEG." The anterior pituitary secretes follicle-stimulating hormone, luteinizing hormone, adrenocorticotropic hormone, thyroid-stimulating hormone, prolactin, endorphins, and growth hormone.
Which of the following correctly matches a gland to the function of a hormone it releases?
Posterior pituitary releases a hormone to cause water retention in kidneys
Posterior pituitary releases a hormone to cause follicle development
Anterior pituitary releases a hormone to cause uterine contractions
Parathyroid releases a hormone to reduce blood calcium
Adrenal cortex releases a hormone to raise blood glucose
The posterior pituitary releases antidiuretic hormone (vasopressin), which causes water retention in the kidneys, making this the correct answer.
Follicle-stimulating hormone causes follicle development, and is released from the anterior (not the posterior) pituitary.
Oxytocin causes uterine contractions, and is released from the posterior (not the anterior) pituitary.
Calcitonin helps to reduce blood calcium, and is released from the thyroid. Parathyroid hormone acts counter to calcitonin, and increases blood calcium.
Glucagon helps to increase blood glucose levels by stimulating glycogen break-down, and is released from the pancreas (not the adrenal gland).
Select the correct pairing of gland and hormone.
Posterior pituitary secretes oxytocin
Adrenal cortex secretes calcitonin
Thyroid secretes cortisol
Adrenal medulla secretes aldosterone
The posterior pituitary secretes oxytocin, which is important for milk ejection from breasts and uterine contractions during labor.
Calcitonin, which serves to decrease serum calcium, is secreted by the thyroid gland. The adrenal cortex secretes aldosterone, which increases blood pressure by increasing sodium reabsorption and potassium secretion. The adrenal cortex also secretes cortisol, a steroid hormone that acts to increase serum glucose, aid in fat, protein, and carbohydrate metabolism, and suppress the body's immune system.
Which of the following hormones is not produced by the anterior pituitary gland?
Oxytocin
Growth hormone
Follicle-stimulating hormone
Prolactin
Oxytocin is produced by the hypothalamus and stored in the posterior pituitary gland. Upon stimulation, oxytocin is released from the posterior pituitary to cause lactation and uterine contractions during pregnancy, though it has also been linked to some social phenomena.
Growth hormone, follicle-stimulating hormone, and prolactin are produced and secreted from the anterior pituitary gland. Growth hormone promotes bone elongation and cell division. Follicle-stimulating hormone works to regulate the menstrual cycle. Prolactin stimulates milk production, while oxytocin stimulates the actual act of lactation.
Which of these hormones is correctly paired with the endocrine organ that releases it into the bloodstream?
Oxytocin, posterior pituitary
Thyroid-stimulating hormone (TSH), thyroid
ADH (antidiuretic hormone), hypothalamus
Adrenal glands, calcitonin
Aldosterone, anterior pituitary
Oxytocin is produced by the hypothalamus, but stored and released by the posterior pituitary, making it the correct answer. Antidiuretic hormone (ADH) is also released by the posterior pituitary, so its pairing with the hypothalamus was incorrect. Calcitonin is released by the thyroid, and aldosterone (like other corticosteroids) is released by the adrenal cortex. Thyroid-stimulating hormone (TSH) is released from the anterior pituitary.
Which of the following statements is false?
Oxytocin is created in the posterior pituitary gland
Follicle-stimulating hormone is created in the anterior pituitary gland
Glucagon is created in the pancreas
Aldosterone is created in the adrenal cortex
The posterior pituitary gland does in fact secrete oxytocin; however, all of the hormones secreted by the posterior pituitary gland are created in the hypothalamus. The hormones are then sent to the posterior pituitary gland in order to be secreted.
The anterior pituitary creates and secretes follicle-stimulating hormone. The pancreas creates and secretes glucagon and insulin. The adrenal cortex creates and secretes aldosterone.
A researcher is analyzing an individual with dwarfism who has a height of 4’6”. Which of the following is likely true regarding this individual?
The hGH is not synthesized properly in the anterior pituitary gland
The hGH is not synthesized properly in the hypothalamus
The LH is not synthesized properly in the hypothalamus
The LH is not synthesized properly in the anterior pituitary gland
A major player in a growing person is the human growth hormone (hGH). hGH is a peptide hormone released from the anterior pituitary gland. Recall that the hormones secreted from the anterior pituitary gland are synthesized in the gland itself. It receives signaling hormones from the hypothalamus which tells the anterior pituitary gland to start synthesizing a particular hormone. In the case of hGH, hypothalamus releases GHRH (growth hormone releasing hormone) which signals the anterior pituitary to signal and release hGH. Since this person has a short stature, the person likely has a problem with synthesis or release of hGH from anterior pituitary gland.
Which of the following hormones is NOT secreted by the pituitary gland?
Glucagon
Follicle-stimulating hormone
Oxytocin
Antidiuretic hormone
Luteinizing hormone
The correct answer is glucagon. Glucagon is secreted by the pancreas, not the pituitary gland. All the other answer choices are major hormones secreted by the pituitary that are essential to bodily functions.
The hypothalamus uses two specialized types of neuron to stimulate the pituitary. Magnocellular neurons carry hormones directly to the posterior pituitary. Parvocellular neurons secrete hormones into the hypophyseal portal system, where they are delivered to the anterior pituitary.
Which of the following hormones is not secreted by the parvocellular neurons of the hypothalamus?
Vasopressin
All of these are secreted by parvocellular neurons
The parvocellular neurons of the hypothalamus are responsible for secreting numerous hormones into the portal system, which are then delivered to the anterior pituitary. Thyrotropin-releasing hormone (TRH) and corticotropin-releasing hormone (CRH) are released from the parvocellular neurons. TRH stimulates the release of thyroid-stimulating hormone from the anterior pituitary, while CRH stimulates the release of adrenocorticotropic hormone from the anterior pituitary.
Vasopressin and oxytocin are secreted from the magnocellular neurons of the hypothalamus, and are released from the posterior pituitary.
The posterior pituitary is responsible for secreting which of the following hormones?
Oxytocin
Adrenocorticotropic hormone
Thyroid-stimulating hormone
Follicle-stimulating hormone
The posterior pituitary is under neuronal control and is responsible for releasing vasopressin (antidiuretic hormone) and oxytocin.
In contrast, the anterior pituitary is under hormonal control from the hypothalamus, and is responsible for releasing growth hormone, adrenocorticotropic hormone, thyroid-stimulating hormone, follicle-stimulating hormone, luteinizing hormone, and prolactin.