During spermatogenesis, one spermatogonia will become 4 separate functioning spermatozoa. In oogenesis, a primary oocyte will become 1 functioning ovum (or egg) while 3 polar bodies are also produced, which are nonfunctioning and never become eggs.

When a female ovulates, the oocyte is in metaphase II, until it becomes fertilized by a sperm. It then completes the second phase of meiosis to make a mature ovum. Remember that, unlike spermatogenesis, oogenesis begins during development. All oocytes undergo meiosis I during fetal development, and are kept suspended in prophase II until ovulation, when they shift to metaphase II. Meiosis only continues beyond metapahse II if fertilization occurs.

Oogenisis halts in the female embryo while the oocytes are trapped in meiosis II. At the beginning of the menstrual cycle a number of oocytes in primordial follicles are stimulated by pituitary gonadotropins to continue maturation.