Understanding Oogenesis

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Biology › Understanding Oogenesis

Questions 1 - 10
1

Which of the following best defines oogenesis?

The formation of egg cells through meiosis

The inability to form egg cells during meiosis

The inability to form egg cells during mitosis

The formation of egg cells during prophase

The formation of egg cells during anaphase

Explanation

Gametes are formed during the process of meiosis. Oogenesis is the process by which the female games are produced, which occurs in the ovary. The product of oogenesis is one mature egg from one primary oocyte; this occurs about once every four weeks in humans.

2

Which of the following choices correctly lists the order of development of the listed cell types of oogenesis in humans?

Primary oocyte

Secondary oocyte

Oogonium

Ovum

Oogonium, primary oocyte, secondary oocyte, and ovum

Primary oocyte, secondary oocyte, oogonium, and ovum

Oogonium, secondary oocyte, primary oocyte, and ovum

Ovum, primary oocyte, secondary oocyte, and oogonium

Secondary oocyte, primary oocyte, oogonium, and ovum

Explanation

Oogonia are the primordial oocytes formed inside females either during or shortly after birth. At this time, the formation of primary oocytes occurs during dictyate, which lasts until the surge of luteinizing hormone (LH) just before the onset of puberty. After menarche, a few of these cells will further develop each period into secondary oocytes, which are halted in metaphase II until fertilization. At the end of meiosis II, both polar bodies created to discard extra haploid sets of chromosomes disintegrate, leaving behind the oocyte which can then mature into an ovum. Thus, the correct order is the following order: oogonium, primary oocyte, secondary oocyte, and ovum.

3

Where does fertilization of the ovum typically occur?

Fallopian tube

Ovary

Uterus

Cervix

Follicle

Explanation

Fertilization typically occurs in the fallopian tube. After fertilization, the diploid zygote will begin the process of implantation into the uterus, where it undergoes mitotic divisions. The resulting multicellular organism is called the embryo, which further develops in the uterus into a fetus.

4

Many secondary processes enable the primary processes of human gametogenesis to occur smoothly. One important secondary process during human oogenesis is ovarian follicle atresia.

Which of the following is closest to the definition of "ovarian follicle atresia"?

The process by which all but one primary ovarian follicle degenerates and are absorbed back into the ovary, allowing the surviving follicle body to develop into a corpus luteum following ovulation.

The process by which FSH triggers the development of primary follicles into secondary follicles which are ready for ovulation.

The process by which estradiol and luteinizing hormone interact in a positive feedback loop, severely heightening the level of LH and developing the secondary follicle into a tertiary follicle.

The process by which a follicle develops into a corpus luteum following ovulation, which will later release the hormone progesterone into the body.

The process by which the dominant follicle releases large amounts of estradiol during the late follicular phase, preparing the follicle for the LH surge.

Explanation

Follicular atresia is a hormone-controlled, apoptotic (cell-suicide) process by which immature follicles degenerate and are resorbed into the main body of the ovary, leaving one out of typically 20 primary follicles standing as a secondary follicle. This process, moderated by follicle stimulating hormone and tumor necrosis factor alpha (TNF), assists the body in forming the corpus luteum out of the remaining follicle following ovulation, as the body would otherwise not be able to generate enough progesterone to continue the process.

5

Where does oocyte development occur in humans?

Ovaries

Uterus

Fallopian tubes

Placenta

Cervix

Explanation

An oocyte develops in the ovaries during female gametogenesis. If the oocyte eventually becomes an ovum and is fertilized in the fallopian tubes, the resulting gamete will be implanted in the uterus. The placenta is an organ that connects the developing fetus to the uterine wall, and the cervix is the lower portion of the uterus that separates the vagina from the uterus.

6

Each ovum is __________, containing __________, set(s) of chromosomes.

haploid . . . one

haploid . . . two

diploid . . . one

diploid . . . two

polyploid . . . four

Explanation

After completing meiosis II, ova are haploid cells containing one chromosome. Haploid cells have half the number of chromosomes (n) as a diploid cell. Haploid cells like ova and sperm will merge during fertilization and form a diploid cell with two complete sets of chromosomes (2n).

7

The release of a secondary oocyte from the ovary is known as __________.

ovulation

menstruation

oogenesis

meiosis

gametogenesis

Explanation

The release of the secondary oocyte from the ovaries is ovulation. This occurs after the follicles surrounding the oocyte mature and rupture, releasing the cell to be available for fertilization. Menstruation occurs after ovulation - if the ovum fails to be fertilized, the uterus will shed its lining. Oogenesis, the creation of an ovum, is the female form of gametogenesis (creation of a gamete). Meiosis is the process of cell division in which the number of chromosomes is halved.

8

Prior to the onset of menstruation, the development of primary oocytes is paused in what phase of meiosis?

Prophase I

Prophase II

Metaphase I

Anaphase I

Metaphase II

Explanation

Primary oocytes enter meiosis I and replicate their genomes, but they do not make their first meiotic division. They remain in prophase I until a female begins her first menstrual cycle. Then, each month, one primary oocyte resumes the process of meiotic division.

9

After a follicle matures and a primary oocyte completes its first meiotic division, the primary oocyte becomes __________.

a secondary oocyte

an embryo

a gamete

an ovary

a fetus

Explanation

A primary oocyte becomes a secondary oocyte when the follicle grows and matures and the primary oocyte completes its first meiotic division. Shortly after, the follicle will rupture and release the secondary oocyte to be fertilized. Later, after the oocyte develops into an ovum and is fertilized, it becomes a diploid zygote, which develops into an embryo through the process of mitosis. The ovary is the reproductive organ where the ova are produced, and a gamete is the haploid cell (ovum or sperm) that is fertilized and forms a zygote.

10

How many chromosomes does a normal human gamete have?

Explanation

When gametes join they form a cell called a zygote. Human sperm and eggs contain 23 chromosomes. Human zygotes contain 46 chromosomes. The type of cell division that produces gametes with half the normal chromosomes is called meiosis.

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