Monosaccharides and Carbohydrates

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Biochemistry › Monosaccharides and Carbohydrates

Questions 1 - 10
1

A 15 year old male presents with a history of abdominal distention and diarrhea after consuming milk and other products rich in dairy. A deficiency of which enzyme is likely present in this individual?

Lactase

Amylase

Salivase

Frucktokinase

Galactokinase

Explanation

Lactase deficiency is common in humans, particularly those of European descent. Without this enzyme, products containing the sugar lactose cannot be broken down. When lactose cannot be digested, it serves as an osmotic agent in the intestines resulting in abdominal distention and subsequent diarrhea.

2

Which of the following sugars is known as common table sugar?

Sucrose

Fructose

Glucose

Maltose

Explanation

The sugar we eat, or table sugar, is known as sucrose. It is a disaccharide made of one molecule each of glucose and fructose.

Fructose is "fruit sugar." It is a monosaccharide found in honey, fruits, and flowers. Glucose is "blood sugar." It is a monosaccharide that is (like the name suggests) found in our blood. Maltose is "malt sugar." It is a disaccharide formed from two molecules of glucose. It is found in seeds such as barley and is also produced when glucose is caramelized.

3

Most mammals are unable to metabolize which of the following disaccharides?

Cellobiose and lactose

Cellobiose only

Lactose only

Sucrose only

Maltose and sucrose

Explanation

Most mammals are unable to digest beta glycosidic bonds, such as the bonds in cellobiose and lactose. Maltose and sucrose both are connected via alpha glycosidic bonds, and can be digested by mammals.

Note: Most mammals are unable to digest lactose after infancy. It is only through a genetic mutation that many humans now are able to ingest lactose well into adulthood.

4

What two sugars is lactose composed of?

Glucose and galactose

Glucose and glucose

Glucose and fructose

Glucose and sucrose

Galactose and sucrose

Explanation

Three common simple sugars are: glucose, fructose, and galactose. Combining these simple sugars leads to the formation of more complex sugar molecules. Glucose and fructose make sucrose. Glucose and galactose make lactose. Two glucose molecules make maltose.

5

Which of these cannot be digested by mammals?

Cellulose

Lactose

Sucrose

Maltose

Explanation

Maltose is a disaccharide formed from two glucose molecules. Mammals use the enzyme maltase to digest maltose. Lactose is a disaccharide formed from one glucose and one galactose molecule. Mammals use the enzyme lactase to digest lactose. Sucrose is a disaccharide formed from one glucose and one fructose molecule. Mammals use the enzyme sucrase to digest sucrose. Mammals cannot digest cellulose because they do not have the necessary enzymes to do so in their digestive tracts.

6

Disaccharidases are enzymes found in the small intestine that participate in degradation of disaccharides. Which of the following molecules can be broken down by these enzymes?

I. Fructose

II. Sucrose

III. Starch

II only

I only

I and III

II and III

Explanation

Sucrose is a disaccharide that is made up of a glucose and a fructose molecule, bound by a glycosidic linkage. A disaccahridase, called sucrase, breaks down sucrose molecules into their component monosaccharides (glucose and fructose), which can then by absorbed by the enterocytes in the small intestine.

Fructose is a monosaccharide that can be directly absorbed by enterocytes. Starch is a complex carbohydrate (polysaccharide) with many glucose molecules attached via glycosidic bonds.

7

What is a furanose?

A sugar that contains a five-membered ring as part of its cyclical structure

A sugar that contains a six-membered ring as part of its cyclical structure

A six-carbon open-chain sugar

A five-carbon open chain sugar

Explanation

A furanose is defined as a cyclical sugar structure with a five-membered ring. By contrast, a pyranose is a cyclical sugar structure with a six-membered ring.

8

What happens when monosaccharides are bonded together?

Both of these

Oligosaccharides are formed by combining a few monosaccharides.

Polysaccharides are formed by combining many monosaccharides.

Neither of these

Explanation

"Oligo-" is a prefix which means "few." "Poly-" is a prefix which means "many." Just as the names suggest, combining a few monosaccharides leads to the formation of _oligo_saccharides. In the same way, combining many monosaccharides leads to the formation of _poly_saccharides.

9

Which of the following is true about beta-linked polysaccharides?

All of these answers

They are harder to break down than polysaccharides with alpha linkages

They contribute to the structure of bacterial cell walls

They can pack into tight crystalline conformations

None of these answers

Explanation

Beta-linked polysaccharides are tougher to break down than alpha-linked polysaccharides. This feature makes beta-linked polysaccharides a key component in the cell walls of many bacteria such as peptidoglycan. For even more added structure, beta-linked polysaccharides can also pack into tight crystalline conformations (i.e., cellulose in celery stalks). Thus, all of the answer choices are correct.

10

The reaction of D-xylose with sodium borohydride yields which of these?

D-xylitol

L-xylose

D-glucose

D-fructose

D-mannose

Explanation

Reduction of carbonyl groups in aldoses and ketoses gives sugar alcohols.

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