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Master Organic Chemistry

89

TOPICS

18

SECTIONS

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89 skills · 1,660 questions

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89 core skills 100% total weight

01

Addition to Alkynes and Partial Reductions

02

Catalytic Hydrogenation and Reduction Concepts

03

Electrophilic Addition to Alkenes

04

Halogenation and Halohydrin Formation

05

Hydration Reactions (Acid-Catalyzed, Oxymercuration)

06

Hydroboration–Oxidation

07

Ozonolysis and Oxidative Cleavage of Alkenes

08

Addition to Conjugated Dienes

09

Conjugated Dienes and Allylic Stability

10

Diels–Alder Reaction

11

IUPAC Naming: Alkanes and Cycloalkanes

12

IUPAC Naming: Alkenes Alkynes, Alkyl Halides

13

IUPAC Naming: Functional Group Compounds

14

Common Rearrangements (Hydride/Alkyl Shifts)

15

Curved-Arrow Formalism and Mechanistic Bookkeeping

16

Intermediates: Carbocations, Carbanions, Radicals

17

Kinetics vs Thermodynamics in Product Distributions

18

Leaving Groups and Substrate Effects

19

Reaction Coordinate Diagrams and Transition States

20

Multi-Step Synthesis: Functional Group Interconversions

21

Predicting Major Products: Regioselectivity and Stereoselectivity

22

Purification Basics (Extraction, Recrystallization, Distillation)

23

Reaction Conditions and Reagent Recognition

24

Spectroscopy: IR and 1H NMR Recognition

25

Structure Drawing

26

Radical Addition to Alkenes (HBr/Peroxides)

27

Radical Halogenation: Selectivity and Mechanism

28

Chirality and Stereocenters: Identify and Classify

29

Conformational Analysis: Newman Projections

30

Cyclohexane Conformations: Chair, Axial/Equatorial

31

E/Z and Alkene Stereochemistry

32

Enantiomers, Diastereomers, and Meso Compounds

33

R/S Configuration (CIP Rules)

34

Stereochemical Outcomes in Reactions (Stereo/Regio)

35

Acid–Base Concepts (pKa, Conjugates)

36

Aromaticity Basics (Hückel Rule)

37

Functional Groups: Identification and Properties

38

Hybridization, Bonding, and Molecular Geometry

39

Inductive Effects and Electronegativity Trends

40

Nucleophiles and Electrophiles: Recognizing Reactivity

41

Resonance, Formal Charge, and Stability Trends

42

E1 Reactions and Competing Pathways

43

E2 Reactions: Anti-Periplanar Requirement

44

Elimination Products: Zaitsev vs Hofmann

45

SN1 Reactions: Carbocation Stability, Rearrangements

46

SN1/SN2/E1/E2 Decision Framework

47

SN2 Reactions: Conditions, Stereochemistry, Rate

48

Alcohol Oxidation and Functional Group Changes

49

Alcohol Substitution and Elimination

50

Epoxide Opening Reactions

51

Ether Synthesis (Williamson) and Cleavage

52

Aldol Reactions (Addition/Condensation)

53

Alpha-Halogenation and Haloform Reaction

54

Claisen Condensation

55

Keto–Enol Tautomerism and Enolate Formation

56

Michael Addition

57

Amine Alkylation and Reductive Amination

58

Amines: Basicity Trends and Salt Formation

59

Diazonium Chemistry

60

Nucleophilicity vs Basicity: Predicting Behavior

61

Activating/Deactivating Groups and Directing Effects

62

Benzylic Reactions (Oxidation, Radical Bromination)

63

64

Electrophilic Aromatic Substitution (EAS): General Mechanism

65

Nucleophilic Aromatic Substitution (SNAr)

66

Acetal and Hemiacetal Formation

67

Carbonyl Structure and Reactivity (Electrophilicity, Resonance)

68

Hydride Reductions (NaBH4, LiAlH4) and Selectivity

69

Imine and Enamine Formation

70

Nucleophilic Addition to Aldehydes and Ketones

71

Organometallic Additions (Grignard/Organolithium)

72

Acid Chlorides and Anhydrides: Synthesis/Reactions

73

Amide Formation and Hydrolysis

74

Carboxylic Acids and Derivatives: Reactivity Order

75

Esterification and Hydrolysis

76

Nucleophilic Acyl Substitution Mechanism

77

Transesterification

78

Chromatography (TLC/Column): Interpretation and Practice

79

Reaction Workup and Yield Calculations

80

Spectroscopic Verification and Purity Checks

81

13C NMR: Key Signal Patterns

82

1H NMR: Chemical Shift, Splitting, Integration

83

Integrating IR/NMR/MS to Determine Structures

84

IR Spectroscopy: Functional Group Identification

85

Mass Spectrometry: Molecular Ion and Fragmentation

86

Functional Group Interconversions and Reagent Selection

87

Multi-Step Synthesis Planning

88

Protecting Groups (Alcohols/Amines)

89

Retrosynthetic Analysis: Disconnections