Macromolecules

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AP Biology › Macromolecules

Questions 1 - 10
1

Cholesterol is soluble in organic solvents such as chloroform, but is insoluble in water. Based on this information, to which class of macromolecule does cholesterol belong?

Lipid

Enzyme

Nucleic acid

Oligosaccharide

Explanation

Water is a very polar substance that will not interact well with nonpolar macromolecules. Enzymes (proteins), oligosaccharides (carbohydrates), and nucleic acids all contain polar regions that make them soluble in aqueous environments. Lipids, however, are hydrocarbons and generally lack a polar region. Lipids would not be soluble in water, but would be soluble in nonpolar organic solvents, like chloroform. We can conclude that cholesterol is a lipid.

2

Cholesterol is soluble in organic solvents such as chloroform, but is insoluble in water. Based on this information, to which class of macromolecule does cholesterol belong?

Lipid

Enzyme

Nucleic acid

Oligosaccharide

Explanation

Water is a very polar substance that will not interact well with nonpolar macromolecules. Enzymes (proteins), oligosaccharides (carbohydrates), and nucleic acids all contain polar regions that make them soluble in aqueous environments. Lipids, however, are hydrocarbons and generally lack a polar region. Lipids would not be soluble in water, but would be soluble in nonpolar organic solvents, like chloroform. We can conclude that cholesterol is a lipid.

3

ATP and GTP provide energy for several cellular processes, and are composed of all except which of the following components?

A pyrimidine

A pentose sugar

A purine

Three phosphate groups

Explanation

ATP stands for adenosine triphosphate and GTP stands for guanosine triphosphate. Both of them are nucleic acids, meaning that they must contain a pentose sugar, a nitrogenous base, and phosphate groups. Both ATP and GTP contain three phosphate groups. The only difference between ATP and GTP is their nitrogenous base. ATP contains adenine whereas GTP contains guanine. Recall that adenine and guanine are both purines.

ATP and GTP do not contain any pyrimidines (cytosine, thymine, and uracil).

4

ATP and GTP provide energy for several cellular processes, and are composed of all except which of the following components?

A pyrimidine

A pentose sugar

A purine

Three phosphate groups

Explanation

ATP stands for adenosine triphosphate and GTP stands for guanosine triphosphate. Both of them are nucleic acids, meaning that they must contain a pentose sugar, a nitrogenous base, and phosphate groups. Both ATP and GTP contain three phosphate groups. The only difference between ATP and GTP is their nitrogenous base. ATP contains adenine whereas GTP contains guanine. Recall that adenine and guanine are both purines.

ATP and GTP do not contain any pyrimidines (cytosine, thymine, and uracil).

5

Which of the following has both a hydrophobic and hydrophillic portion?

phospholipids

starch

proteins

steriods

chitin

Explanation

A phospholipid has a hydrophobic tail and a hydrophillic head. The hydrocarbon section composes the hydrophobic tail and dislikes water. The phosphate group composes of the hydrophillic head and likes water. The combination makes a semi-permeable membrane that we know as the lipid bilayer.

6

Phospholipids are amphipathic. This means that a phospholipid is __________.

both polar and nonpolar

only soluble in organic solvents

found only in animal cells

a trigger for the immune response

Explanation

Amphipathic molecules have both a polar and nonpolar region. This amphipathic quality allows phospholipids to create the plasma membrane in eukaryotic cells. The polar region is the phosphate head, which interacts with the aqueous cytosol and extracellular environment. The nonpolar region is the fatty acid tail, which is sequestered in the bilayer of the membrane and helps reduce the permeability to certain molecules.

7

Which of the following chemical formulas forms the base of monosaccharides?

Explanation

is the base molecular formula for carbohydrates. Carbohydrates vary based on multiples of this formula (i.e. is the formula for glucose).

8

Which of the following has both a hydrophobic and hydrophillic portion?

phospholipids

starch

proteins

steriods

chitin

Explanation

A phospholipid has a hydrophobic tail and a hydrophillic head. The hydrocarbon section composes the hydrophobic tail and dislikes water. The phosphate group composes of the hydrophillic head and likes water. The combination makes a semi-permeable membrane that we know as the lipid bilayer.

9

Phospholipids are amphipathic. This means that a phospholipid is __________.

both polar and nonpolar

only soluble in organic solvents

found only in animal cells

a trigger for the immune response

Explanation

Amphipathic molecules have both a polar and nonpolar region. This amphipathic quality allows phospholipids to create the plasma membrane in eukaryotic cells. The polar region is the phosphate head, which interacts with the aqueous cytosol and extracellular environment. The nonpolar region is the fatty acid tail, which is sequestered in the bilayer of the membrane and helps reduce the permeability to certain molecules.

10

Which of the following chemical formulas forms the base of monosaccharides?

Explanation

is the base molecular formula for carbohydrates. Carbohydrates vary based on multiples of this formula (i.e. is the formula for glucose).

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