Biology › Understanding Other Cell Structures
Translation is a process that creates protein from mRNA. Where does translation occur in a eukaryotic cell?
Cytosol
Nucleus
Rough endoplasmic reticulum
Golgi apparatus
Recall that the central dogma of molecular biology states that the information flow within a cell involves DNA replication, transcription, and translation. DNA replication involves the formation of two identical DNA molecules from a single molecule and transcription involves synthesis of mRNA from DNA. The DNA molecules can’t leave the nucleus, therefore, both of these processes occur in the nucleus
Translation involves the synthesis of proteins from mRNA molecules. The mRNA molecules exit the nucleus after transcription (through nuclear pores) and enter the cytosol. The ribosomes in the cytosol bind to mRNA and facilitate translation; therefore, translation occurs in the cytosol.
Which organelle is responsible for collecting, packaging, and distributing proteins from the location where they are synthesized to the location where they are used?
Golgi apparatus
Smooth endoplasmic reticulum
Rough endoplasmic reticulum
Lysosome
The golgi apparatus collects, packages and distributes proteins to the locations where they are used. Proteins are always synthesized on ribosomes, which can either be floating in the cytosol, or on the rough endoplasmic reticulum. The smooth endoplasmic reticulum's functions include synthesis of lipids, and detoxification of substances. Lysosomes contain hydrolytic enzymes which break down macromolecules.
What is autophagy?
The process by which malfunctioning and worn out parts of the cell are broken down and recycled
The automatic defensive response that a nucleus initiates when the cell is under attack
The process by which all malfunctioning and worn out parts of the cell are immediately discarded by being pushed out of the cell membrane
The process by which a T-lymphocyte learns to recognize "self" antigens
Eukaryotic cells are very resourceful in every way they function. When a cell part becomes worn out or non-functional, these part is broken down and recycled by the cell via lysosomal activation. This process is known as autophagy. The biological monomers produced from the catabolic process can then be used to build new polymers and macromolecules.
Exocytosis is the process by which contents from within the cell are expelled across the membrane. This generally occurs to assist cell signaling, such as the exocytosis of neurotransmitters. Positive selection is the process by which T-lymphocytes are presented by "self" antigens. If the T-cell reacts to the "self" antigen, it is destroyed to prevent autoimmune reactions.
Which of the following is found at the head of a sperm cell?
The acrosome
The terminal disc
The tail
A dense concentration of mitochondria
The tail, terminal disc, and most mitochondria are found near the rear of the sperm cell (in order to facilitate movement). The acrosome is a cap-like organelle (derived from the Golgi apparatus) that develops over the anterior half of the head in the sperm cells of many animals. The acrosome contains digestive enzymes which allows the break down of the outer membrane of the ovum (zona pellucida). In short, the acrosome is located at the head of the sperm cell and allows penetration of the egg cell.
Ribosomes are found in which domains of life?
All three domains
Bacteria only
Archaea only
Eukarya only
Ribosomes are found in all cell types and in all three domains. Recall the central dogma of biology: DNA RNA
protein. Thus, all cells synthesize proteins using ribosomes. Also, note that although prokaryotes have ribosomes, ribosomes are never membrane-bound. Thus it still holds true that prokaryotes do not have any membrane-bound organelles.
In the endoplasmic reticulum, chains of carbohydrates can be added to proteins. What is the name for such resulting molecules?
Glycoproteins
Phospholipids
mRNA
Lumen
Glycoproteins are proteins that have been modified by the addition of chains of carbohydrates of varying length. Glycosylation of proteins happens in the endoplasmic reticulum and the Golgi apparatus. Phospholipids are not proteins and are thus not synthesized in the endoplasmic reticulum, rather, they are synthesized in the cytosol. mRNA is the nucleic acid product of transcription, which occurs in the cytosol in eukaryotes, and in the cytosol in prokaryotes. Lumen is the term which means "an opening," e.g., the lumen of a blood vessel is the space where the blood flows, the lumen of the endoplasmic reticulum is the space inside the organelle itself.
Why do liver cells have more extensive smooth endoplasmic reticula than most other cells of the body?
They are used to detoxify substances
They make the liver smooth
They are not present in liver cells
They are used to make glycoproteins
One of the functions of the liver is to detoxify certain substances such as alcohol, lactic acid, and drugs. Since the smooth endoplasmic reticulum plays an important role in detoxification, liver cells contain extensive smooth endoplasmic reticula. The process of forming glycoproteins is carried out by the rough endoplasmic reticulum, and to some extent, the Golgi apparatus.
In several important biochemical mechanisms, the cell's enzyme requires a particular enantiomer of a substrate in order to carry out the reaction. Why is this true?
Enzymes are highly specific in terms of shape in order to carry out a reaction
The cell's enzymes have evolved to prefer a particular enantiomer becuase it is more abundant
Enzymes lower the activation energy of a biochemical reaction
Enzymes are highly dependent on temperature
None of the other answer choices
This question requires the knowledge that several biological substrates come in enantiomer forms (think of them as your right and left hands). Effectively these molecules come in two mirror/opposite configurations. Having the right configuration or shape is crucial for enzymes to catalyze reactions due to highly shape-specific bnding sites on substrate molecules. Thus, the correct answer to this qustion is "enzymes are highly specific on shape in order to carry out a reaction." The other answer choices, except "the cell has evolved to prefer a particular enantiomer becuase it is more abundant," do not allude to this underlying concept of why cells need a particualr enantiomeritic form/shape in order to carry out a reaction and are not correct. Last, enantiomers typically appear in similar oncentrations due to equal potential energies; therefore, it is unlikely and incorrect to expect the cell to develop an evolutionary preference based upon abundance.
Which of the following is not considered part of the eukaryotic endomembrane system?
Mitochondria
Endoplasmic reticulum
Golgi body
Vesicle
Cell membrane
The endomembrane system is a collection of membranes making up a cell that are connected either physically or via transport using vesicles. One of its main functions is to package and "ship" things made in the cell to other places in the organism, such as hormones like insulin. In order to do this, different organelles with different functions are necessary, just like there are different people with different jobs who make sure a package is mailed to the proper place.
Where is ribosomal RNA formed?
Nucleolus
Mitochondria
Golgi apparatus
Smooth endoplasmic reticulum
Rough endoplasmic reticulum
The nucleolus is a specialized region found within the nucleus. It is responsible for synthesizing ribosomal RNA (rRNA), while transcription of messenger RNA (mRNA) and transfer RNA (tRNA) occurs in parts of the nucleus other than the nucleolus.