Endocrine and Immune Systems

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NCLEX-PN › Endocrine and Immune Systems

Questions 1 - 10
1

What nutrients are specifically needed for proper thyroid hormone production?

Tyrosine, iodine, and selenium

Methionine and magnesium

Iron, manganese, and biotin

Iodine and manganese

Explanation

The nutrients specifically required for thyroid hormone production are tyrosine, iodine, and selenium, in addition to zinc and several B vitamins. While magnesium, manganese, and methionine are all essential for metabolism and overall hormone production, they are not direct substrates or cofactors in the production of thyroid hormone.

2

What nutrients are specifically needed for proper thyroid hormone production?

Tyrosine, iodine, and selenium

Methionine and magnesium

Iron, manganese, and biotin

Iodine and manganese

Explanation

The nutrients specifically required for thyroid hormone production are tyrosine, iodine, and selenium, in addition to zinc and several B vitamins. While magnesium, manganese, and methionine are all essential for metabolism and overall hormone production, they are not direct substrates or cofactors in the production of thyroid hormone.

3

Which of the following hormones is produced by the adrenal medulla?

Epinephrine

Antidiuretic hormone

Calcitonin

Thyroid-stimulating hormone

Follicle-stimulating hormone

Explanation

Epinephrine is the only hormone of those listed that is produced by the adrenal medulla. The adrenal medulla is the center of the adrenal gland. Antidiuretic hormone is produced by the posterior pituitary. Calcitonin is produced by the thyroid. Thyroid-stimulating hormone is secreted from the anterior pituitary, as is follicle-stimulating hormone.

4

Which of the following hormones is produced by the adrenal medulla?

Epinephrine

Antidiuretic hormone

Calcitonin

Thyroid-stimulating hormone

Follicle-stimulating hormone

Explanation

Epinephrine is the only hormone of those listed that is produced by the adrenal medulla. The adrenal medulla is the center of the adrenal gland. Antidiuretic hormone is produced by the posterior pituitary. Calcitonin is produced by the thyroid. Thyroid-stimulating hormone is secreted from the anterior pituitary, as is follicle-stimulating hormone.

5

Which immune cell is specialized for immunity against multicellular parasites?

Eosinophils

Basophils

Monocytes

Natural killer cells

Explanation

While all of the cells listed may have some indirect involvement in the overall response to a parasitic infection, eosinophils are the only immune cells that are specialized to respond to multicellular parasites, especially helminths such as hookworms and pinworms.

6

Which immune cell is specialized for immunity against multicellular parasites?

Eosinophils

Basophils

Monocytes

Natural killer cells

Explanation

While all of the cells listed may have some indirect involvement in the overall response to a parasitic infection, eosinophils are the only immune cells that are specialized to respond to multicellular parasites, especially helminths such as hookworms and pinworms.

7

Mast cells contain high concentrations of which of the following?

All of these

Histamine

Tryptase

Heparin

Explanation

Mast cells are rich in granules that contain high concentrations of heparin, histamine, and trypsin, among other preformed proteases. These granules also contain serotonin and various eicosanoids. The function of mast cells is primarily to regulate immune (inflammatory) responses to allergens.

8

Mast cells contain high concentrations of which of the following?

All of these

Histamine

Tryptase

Heparin

Explanation

Mast cells are rich in granules that contain high concentrations of heparin, histamine, and trypsin, among other preformed proteases. These granules also contain serotonin and various eicosanoids. The function of mast cells is primarily to regulate immune (inflammatory) responses to allergens.

9

What role do tyrosine and iodine play in thyroid hormone (thyroxine (T4), and triiodothyronine (T3)) production?

Synthesis of T4

Conversion of T4 to T3

Conversion of phenylalanine into tyrosine

None of these

Explanation

Tyrosine and iodine are both precursors for synthesis of T4. Selenium is essential for conversion of T4 to T3, and iron is the cofactor for conversion of phenylalanine into tyrosine.

10

Which of the following would be considered to part of nonspecific immunity?

Macrophages

Plasma cells

Memory cells

CD8 T cells

Explanation

Macrophages, the main blood cells responsible for phagocytosis of debris, bacteria, and virally infected cells, are part of the nonspecific immune response. While they are able to recognize self versus non-self proteins, they are not uniquely sensitive to any particular non-self protein type. Rathe, they phagocytose foreign matter as well as cellular debris. Plasma cells, memory cells, and CD8 T cells are all lymphocytes, and as such they are all part of the adaptive or "specific" immune system, meaning that they are uniquely sensitive to particular pathogenic proteins.

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