Viral Structure And Replication Practice Test

A 28-year-old woman has an abnormal Pap smear showing koilocytotic atypia. Further testing with DNA hybridization confirms an infection with a high-risk strain of human papillomavirus (HPV). The physician explains that this virus can lead to cervical cancer by interfering with the host cell cycle.

A researcher is studying the replication of Poliovirus, a member of the Picornaviridae family. After infecting cultured cells, she observes that host cell protein synthesis is rapidly shut off, and the host ribosomes are used to translate a single, long viral mRNA molecule.