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Mitochondrial And Non-Mendelian Inheritance Practice Test
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Q1
A 10-year-old boy presents with ptosis, ophthalmoplegia, and muscle weakness. A muscle biopsy shows ragged-red fibers. His mother has mild hearing loss and exercise intolerance, but his father is asymptomatic. Molecular testing confirms a large deletion in the mitochondrial DNA.
If this boy grows up and has children with an unaffected woman, what is the likelihood he will pass the mitochondrial DNA deletion to them?
If this boy grows up and has children with an unaffected woman, what is the likelihood he will pass the mitochondrial DNA deletion to them?