Data Interpretation Practice Test

A new rapid diagnostic test for Streptococcus pyogenes pharyngitis is evaluated against the gold standard throat culture. In a study of 300 children with sore throats, 100 have culture-confirmed streptococcal pharyngitis. Of these 100 children, the new rapid test is positive in 80. Of the 200 children with negative throat cultures, the rapid test is positive in 20.

Researchers develop a new serum biomarker to screen for early-stage ovarian cancer. To evaluate its diagnostic performance, they generate a receiver operating characteristic (ROC) curve. The calculated area under the curve (AUC) is 0.91.