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Central Nervous System Pharmacology Practice Test

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Q1

A 45-year-old man with a long history of schizophrenia, previously managed with haloperidol, is switched to a new medication due to persistent negative symptoms. Six months later, his fasting glucose is 135 mg/dL and he has gained 11 kg (25 lb). His psychotic symptoms, however, have improved. The new medication is discontinued due to these metabolic changes.

The beneficial effects and metabolic side effects of this new medication are most likely mediated by its antagonist activity at which combination of receptors?

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