Cancer Genetics Practice Test

A researcher observes that many cancer cells have developed mechanisms to evade apoptosis. One such mechanism involves the inactivation of the p53 tumor suppressor protein, which normally induces apoptosis in response to cellular stress.

A 65-year-old man with a 40-pack-year smoking history presents with a 3-month history of painless jaundice, weight loss, and pruritus. An abdominal CT scan shows a 3-cm mass in the head of the pancreas. Molecular analysis of a tumor biopsy is performed.