Sterile Preparations Practice Test

A 6-year-old male (20 kg) with acute lymphoblastic leukemia is scheduled for vincristine 1.2 mg IV today (hazardous drug). Allergies: none. Labs: SCr 0.4 mg/dL, AST 20 units/L, ALT 16 units/L, WBC 2,100/mm$^3$, platelets 85,000/mm$^3$. Current medications: trimethoprim-sulfamethoxazole 80/400 mg by mouth twice daily on weekends, ondansetron 4 mg by mouth every 8 hours as needed. The dose will be compounded in a negative-pressure ISO Class 7 hazardous buffer room using an ISO Class 5 biological safety cabinet (BSC) and transported to the infusion center. Which personal protective equipment is required for this preparation?

A 76-year-old male (74 kg) with sepsis is ordered norepinephrine 8 mg in 250 mL D5W as a continuous IV infusion. Allergies: none. Labs: SCr 1.8 mg/dL, AST 40 units/L, ALT 33 units/L, WBC 19,000/mm$^3$. Current medications: vasopressin infusion, meropenem 1 g IV every 8 hours. The pharmacy will batch compound multiple norepinephrine bags for the ICU using an ISO Class 5 PEC in an ISO Class 7 buffer room, and store them refrigerated until needed. What is the appropriate beyond-use date for this compound?