Recognition And Management Practice Test

A 45-year-old man (weight 88 kg) with newly diagnosed hypertension is prescribed lisinopril 10 mg once daily. He also takes ibuprofen 600 mg three times daily for chronic back pain and hydrochlorothiazide 25 mg once daily. Baseline labs: serum creatinine 1.1 mg/dL, potassium 4.7 mEq/L, alanine aminotransferase 24 U/L. Allergies: none. Which monitoring parameter should be prioritized after starting lisinopril in this patient?

A 73-year-old woman (weight 54 kg) is seen in clinic for therapy optimization of hyperlipidemia. Current medications: amlodipine 10 mg once daily and simvastatin 40 mg nightly. Labs: alanine aminotransferase 32 U/L, serum creatinine 0.9 mg/dL; she reports new muscle aches but no dark urine. Allergies: none. Medical history includes hypertension and coronary artery disease. Which medication change is most appropriate for this patient?