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Monitoring Parameters (Labs And Vitals) Practice Test

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A 61-year-old male (85 kg) with rheumatoid arthritis is taking methotrexate 15 mg PO once weekly with folic acid 1 mg PO daily. Current medications: methotrexate, folic acid, omeprazole 20 mg PO daily. Allergies: none. Labs today: AST 78 U/L (10–40), ALT 92 U/L (7–56), SCr 1.0 mg/dL (0.6–1.2), platelets 210 $×10^3$/mm³ (150–450). Vital signs: BP 124/76 mmHg, HR 74 bpm. Which lab result suggests a need for intervention related to his current therapy?

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