All questions
Question 1
As I stepped into the hospital room that morning, I was struck not by the complexity of the medical equipment or the sterile environment, but by something far more profound. Mrs. Chen, an 82-year-old woman recovering from hip surgery, was teaching her nurse how to fold origami cranes. Her weathered hands, still steady despite her age, guided the young nurse's fingers as they transformed simple paper into delicate art. 'In my culture,' she explained softly, 'we believe that if you fold one thousand cranes, your wish will come true. I'm not wishing for myself anymore—I'm wishing for all the people in this place to find peace.' The nurse, initially hesitant about this interruption to her routine, found herself completely absorbed in the meditative process. Other staff members began stopping by, drawn by the quiet dignity of this simple act of hope.
The author's tone in describing this hospital scene is best characterized as:
- Clinically detached and focused primarily on documenting medical procedures and patient care protocols in healthcare settings
- Reverently appreciative of an unexpected moment of grace and human connection transcending the institutional environment (correct answer)
- Sentimentally nostalgic about traditional cultural practices and concerned about their disappearance in modern healthcare contexts
- Critically analytical of hospital efficiency and questioning whether non-medical activities should be permitted during patient care
Explanation: The author's tone is reverently appreciative, showing deep respect for Mrs. Chen's dignified act and its transformative effect on the hospital environment. Words like 'profound,' 'quiet dignity,' and the focus on how this simple act draws others suggest reverence and appreciation for unexpected grace. Choice A is incorrect because the tone is warm and personal, not clinically detached. Choice C is incorrect because the focus is on the present moment's beauty rather than nostalgia for the past. Choice D is incorrect because there's no criticism of hospital efficiency; instead, the author celebrates this meaningful interruption.
Question 2
Scurvy, a disease resulting from a deficiency of vitamin C, was historically a major peril for sailors on long voyages. The condition manifested with weakness, gum disease, and poor wound healing. For centuries, its cause was a mystery. In 1747, James Lind, a Royal Navy surgeon, conducted one of the first controlled clinical trials. He divided 12 scorbutic sailors into six groups, giving each a different dietary supplement. The group given citrus fruits—oranges and lemons—showed a dramatic recovery. While it took the British Admiralty decades to implement Lind's findings by mandating lemon or lime juice for its sailors, his work laid the foundation for modern evidence-based medicine and the understanding of nutritional deficiencies.
What is the author's primary purpose in writing this passage?
- To provide a detailed biography of James Lind
- To argue for the superiority of citrus fruits over other supplements
- To describe the symptoms of scurvy in extensive clinical detail
- To recount the historical discovery of the cure for scurvy (correct answer)
Explanation: When you encounter a question asking about an author's primary purpose, focus on the passage's overall structure and what the author spends most time discussing. Look for the main thread that connects all the information presented.
This passage follows a clear historical narrative: it introduces scurvy as a mysterious disease that plagued sailors, then describes James Lind's groundbreaking 1747 experiment that identified citrus fruits as the cure, and concludes with the broader impact of his discovery. The author is telling the story of how scurvy's cure was discovered through scientific experimentation.
Choice D correctly captures this primary purpose—the passage recounts the historical sequence of events leading to scurvy's cure, from the problem identification through Lind's experiment to the eventual implementation of his findings.
Choice A is incorrect because while James Lind is mentioned, the passage provides minimal biographical details about him personally. The focus is on his specific experiment and its significance, not his life story.
Choice B misses the mark because the author isn't arguing for citrus fruits' superiority. Instead, the passage objectively reports that Lind's experiment demonstrated their effectiveness—this is historical fact-telling, not persuasive writing.
Choice C is wrong because scurvy symptoms receive only brief mention in the opening sentence. The passage quickly moves past symptoms to focus on the discovery of the cure.
For HESI reading questions about author's purpose, identify what takes up the most "real estate" in the passage. The primary purpose should account for the majority of the content, not just isolated details or supporting information.
Question 3
The placebo effect remains one of the most fascinating and confounding phenomena in medicine. It occurs when a patient experiences real physiological or psychological improvements after receiving a treatment with no active therapeutic element, such as a sugar pill. Studies have shown placebos can alleviate pain, depression, and fatigue. This is not merely 'in the mind'; brain imaging has revealed that placebos can trigger the release of endogenous opioids, the body's natural painkillers. Understanding the mechanisms behind this powerful effect could unlock new pathways for treatment that harness the body's innate healing capabilities.
What is the author's main purpose for writing this passage?
- To persuade patients to request placebo treatments from their doctors
- To inform the reader about the nature and significance of the placebo effect (correct answer)
- To criticize the use of inactive substances in clinical research trials
- To argue that most conventional medicines are no better than sugar pills
Explanation: When analyzing author's purpose questions, focus on the overall tone and structure of the passage to determine what the author is trying to accomplish.
This passage takes an informational, educational approach to explaining the placebo effect. The author systematically defines what placebos are, describes their documented effects, explains the scientific evidence behind them (including brain imaging studies), and discusses their potential significance for future medicine. The neutral, explanatory tone suggests the author wants to teach readers about this phenomenon rather than advocate for any particular position.
Choice B correctly identifies this informational purpose. The author presents factual information about placebos in a balanced way, helping readers understand both what the effect is and why it matters scientifically.
Choice A is wrong because the author never suggests patients should seek placebo treatments. The passage focuses on understanding the phenomenon, not recommending specific actions for patients.
Choice C misses the mark entirely—there's no criticism of research practices here. Instead, the author presents research findings positively as evidence of placebo effects.
Choice D represents a major misinterpretation. The author never compares placebos to conventional medicines or suggests that regular medications are ineffective. The focus remains solely on understanding how placebos work.
For HESI reading questions about author's purpose, pay attention to the overall tone and ask yourself: Is the author trying to inform, persuade, entertain, or criticize? The neutral, fact-based presentation here clearly indicates an informational purpose.
Question 4
Consider the human heart: a fist-sized organ that tirelessly beats over 100,000 times a day, pumping blood through an intricate network of vessels stretching 60,000 miles. Its four chambers work in perfect, rhythmic coordination, a symphony of valves opening and closing to ensure that oxygenated blood reaches every cell. This remarkable biological machine functions without conscious thought, sustaining life from its earliest moments to its last. The sheer elegance and efficiency of its design are a testament to the marvels of physiological engineering.
The author's tone in this passage can best be described as which of the following?
- Clinically detached
- Appreciative and admiring (correct answer)
- Confused and questioning
- Simplistic and condescending
Explanation: When analyzing an author's tone in reading comprehension passages, you need to identify the emotional attitude or perspective the writer conveys toward their subject matter through word choice and descriptive language.
Looking at this passage about the heart, the author uses distinctly positive and reverent language throughout. Words like "remarkable," "perfect," "symphony," "elegance," and "marvels" all signal deep appreciation. The author presents the heart not just as a biological organ, but as something worthy of wonder and admiration. Phrases like "sheer elegance and efficiency" and "testament to the marvels of physiological engineering" clearly demonstrate an appreciative, admiring tone, making B the correct answer.
Let's examine why the other options don't fit: A) Clinically detached would involve neutral, objective language without emotional investment—but this passage is full of admiring adjectives and metaphors. C) Confused and questioning would include uncertain language, questions, or expressions of bewilderment, which are completely absent here. D) Simplistic and condescending would talk down to readers or oversimplify complex topics in a patronizing way, but the author treats the subject with respect and uses sophisticated vocabulary.
For HESI reading passages, pay close attention to adjectives and descriptive phrases—they're your biggest clues to tone. Authors rarely state their attitudes directly; instead, they reveal them through word choice. When you see consistently positive, wonder-filled language like "symphony," "remarkable," and "marvels," you're looking at an appreciative tone.
Question 5
Mandatory annual influenza vaccination for all healthcare personnel is a critical patient safety measure. While some professionals object on the grounds of personal autonomy, this perspective overlooks the ethical obligation to 'first, do no harm.' Healthcare workers have a significantly higher risk of acquiring and transmitting influenza to their vulnerable patients, including the immunocompromised and the elderly. Numerous studies have demonstrated that higher vaccination rates among staff lead to lower rates of healthcare-associated influenza. Therefore, institutional policies requiring vaccination are not a matter of personal choice, but a professional and ethical necessity.
The author's primary purpose in this passage is to:
- Present a neutral overview of the debate surrounding mandatory vaccinations
- Inform healthcare workers about the biological mechanism of the flu vaccine
- Advocate for a specific policy based on an ethical and safety argument (correct answer)
- Analyze the results of studies on healthcare-associated influenza rates
Explanation: When you encounter reading comprehension questions about an author's primary purpose, focus on the overall goal and tone of the passage rather than getting distracted by specific details or examples mentioned along the way.
This passage takes a clear argumentative stance from the beginning. The author presents mandatory flu vaccination as "critical" and "necessary," then systematically builds a case using ethical principles ("first, do no harm") and scientific evidence (studies showing reduced transmission rates). The language is persuasive, not neutral, as the author explicitly argues that vaccination policies are "not a matter of personal choice, but a professional and ethical necessity."
Choice C correctly identifies this advocacy approach. The author isn't just discussing the topic—they're actively promoting mandatory vaccination policies by combining ethical obligations with patient safety data.
Choice A is incorrect because the passage is clearly one-sided, not neutral. The author dismisses objections based on personal autonomy and doesn't present both sides equally. Choice B misses the mark entirely—while vaccination is mentioned, there's no explanation of biological mechanisms or how vaccines work. Choice D is wrong because although studies are referenced, they're used as supporting evidence rather than being analyzed in detail. The studies serve the larger argumentative purpose.
For HESI reading questions about author's purpose, look for the dominant tone and overall message. Ask yourself: "Is the author trying to convince me of something, inform me neutrally, or analyze data objectively?" Strong language like "critical," "necessity," and "obligation" signals advocacy rather than neutral information-sharing.
Question 6
The classification of living organisms, known as taxonomy, has undergone significant revision. The traditional five-kingdom system (Monera, Protista, Fungi, Plantae, Animalia) was based largely on observable morphological characteristics. However, with the advent of genetic sequencing, scientists can now compare organisms at the molecular level. This has led to the development of the three-domain system (Bacteria, Archaea, and Eukarya), which reflects a deeper understanding of evolutionary relationships. For example, Archaea, once grouped with bacteria in Monera, are now known to be as genetically different from bacteria as they are from eukaryotes.
What is the author's tone in this passage?
- Argumentative
- Explanatory (correct answer)
- Skeptical
- Biased
Explanation: When you encounter tone questions on reading passages, you need to identify the author's attitude and approach toward the subject matter. Look for clues in word choice, sentence structure, and overall purpose.
This passage maintains an explanatory tone throughout. The author presents factual information about how biological classification systems have evolved, using neutral language like "has undergone significant revision" and "scientists can now compare organisms." The writing follows a clear informational structure: introducing the traditional system, explaining what caused changes, and providing specific examples. There's no emotional language or persuasive elements—just straightforward presentation of scientific developments.
Let's examine why the other options don't fit. Choice A (Argumentative) is incorrect because the author isn't trying to convince you of a particular viewpoint or debate a controversial issue—they're simply explaining how classification systems changed based on new technology. Choice C (Skeptical) doesn't work because the author shows no doubt or questioning attitude toward the information presented; instead, they accept and explain the scientific developments as factual. Choice D (Biased) is wrong because the passage shows no favoritism or prejudice—the author presents both the old and new systems objectively without suggesting one is inherently better.
The correct answer is B (Explanatory) because the author's primary purpose is to inform and educate readers about changes in biological classification.
For HESI reading questions about tone, focus on the author's purpose and emotional stance. Explanatory passages teach without arguing, while argumentative ones try to persuade. Look for neutral versus charged language to distinguish between them.
Question 7
A recent study published in a prominent medical journal suggested a link between a popular artificial sweetener and an increased risk of cardiovascular events. While the media has sensationalized these findings, it is crucial to examine the study's methodology. The research was observational, meaning it can only identify a correlation, not a causal relationship. Furthermore, the participant group that consumed high amounts of the sweetener also exhibited other high-risk behaviors, such as lower physical activity and higher caloric intake, which were not fully accounted for. Therefore, proclaiming this sweetener as dangerous based on this single study is a premature and potentially misleading conclusion.
The author's purpose is to:
- Summarize the findings of a new medical study for the public
- Encourage the public to immediately stop consuming artificial sweeteners
- Critique the study's limitations and caution against misinterpretation (correct answer)
- Praise the media for raising awareness about potential health risks
Explanation: When you encounter reading comprehension questions about author's purpose, look for key phrases and the overall tone to understand what the author is trying to accomplish. This passage discusses a medical study but takes a critical stance toward how it's being interpreted.
The author's main purpose is to critique the study's limitations and warn against misinterpretation. Notice the critical language: "sensationalized," "crucial to examine," and "premature and potentially misleading conclusion." The author systematically identifies flaws in the research methodology, explaining that observational studies can only show correlation, not causation, and that confounding variables weren't properly controlled. The entire passage builds an argument for caution rather than panic.
Let's examine why the other options miss the mark. Choice A is incorrect because the author doesn't simply summarize findings—they actively critique the study's validity and media coverage. Choice B is wrong because the author never advises people to stop using artificial sweeteners; instead, they argue against rushing to conclusions. Choice D misses the point entirely since the author criticizes the media for "sensationalizing" the findings, not praising them for awareness.
The correct answer is C because the author systematically points out methodological flaws and warns against drawing premature conclusions from limited evidence.
For HESI reading questions about author's purpose, pay attention to the author's tone and approach. Are they informing, persuading, criticizing, or explaining? Look for evaluative language that reveals the author's stance—words like "crucial," "premature," or "misleading" signal critical analysis rather than neutral reporting.
Question 8
Burnout among nurses is reaching epidemic levels, characterized by emotional exhaustion, depersonalization, and a reduced sense of personal accomplishment. The causes are multifaceted, including excessive workloads, long hours, and the emotional toll of patient care. This is not just a personal issue for the nurse; it directly impacts patient safety, leading to higher rates of medical errors and lower patient satisfaction. Hospitals and healthcare systems must move beyond superficial wellness initiatives and address the systemic problems. Meaningful solutions include enforcing safe nurse-to-patient ratios, providing genuine mental health support, and fostering a culture that values the well-being of its staff.
Which of the following best describes the author's purpose?
- To describe the personal experiences of a single nurse suffering from burnout
- To define the term 'burnout' from a purely academic perspective
- To identify a problem and advocate for specific systemic solutions (correct answer)
- To compare burnout rates between nurses and other medical professionals
Explanation: When you encounter reading comprehension questions asking about an author's purpose, look for the overall intent behind the passage rather than getting caught up in individual details or examples mentioned along the way.
This passage follows a classic problem-solution structure. The author begins by identifying nurse burnout as an "epidemic" with serious consequences, then transitions to advocating for "meaningful solutions" including specific systemic changes like enforcing safe nurse-to-patient ratios and providing mental health support. The phrase "hospitals and healthcare systems must move beyond superficial wellness initiatives" clearly signals the author's advocacy stance, pushing for concrete action rather than just describing a problem.
Choice C correctly captures this dual purpose: identifying the problem (nurse burnout and its impacts) while advocating for specific systemic solutions (the detailed recommendations in the final sentence).
Choice A is too narrow—while the passage mentions nurses' experiences, it doesn't focus on a single individual's story but rather addresses the broader issue affecting the profession. Choice B misses the advocacy element entirely; the author goes far beyond academic definition to push for change. Choice D is incorrect because the passage never compares nurses to other medical professionals—it focuses exclusively on the nursing profession.
For HESI reading questions about author's purpose, look for action words like "must," "should," or "need to" that signal advocacy, and pay attention to passage structure. Authors who present problems followed by solutions are typically advocating for change, not just informing or describing.
Question 9
Homeostasis is the physiological process by which the body maintains a stable internal environment despite external changes. Consider thermoregulation: if body temperature rises, the hypothalamus triggers sweating to cool the body down. If it drops, it initiates shivering to generate heat. Similar feedback mechanisms regulate blood sugar, pH levels, and fluid balance. This constant, dynamic equilibrium is not just important; it is the very foundation of health and life. Any significant or prolonged disruption to homeostasis can lead to disease or death.
The author's tone throughout this passage is best described as:
- Formal and instructive (correct answer)
- Casual and conversational
- Alarmist and exaggerated
- Speculative and uncertain
Explanation: When analyzing an author's tone in reading comprehension questions, you need to examine the language choices, sentence structure, and overall approach the writer takes toward their subject matter.
This passage demonstrates a formal and instructive tone through several key indicators. The author uses precise scientific terminology like "physiological process," "hypothalamus," and "dynamic equilibrium" without defining these terms, suggesting an academic writing style. The sentence structure is complex and carefully constructed, with clear explanations that build upon each other systematically. The author presents factual information in a teaching manner, moving from a general definition to specific examples (thermoregulation) and then to broader applications, which is characteristic of educational writing.
Answer choice B is incorrect because the language remains consistently formal throughout—there are no contractions, colloquialisms, or informal expressions that would indicate a casual tone. Choice C is wrong because while the author mentions serious consequences ("disease or death"), the overall presentation is measured and factual rather than sensationalized or fear-inducing. The author simply states biological realities without emotional language. Choice D is incorrect because the author presents information as established fact using definitive language like "is the physiological process" and "Any significant disruption can lead to," showing certainty rather than speculation.
For HESI reading questions about tone, focus on the author's word choice and certainty level. Formal writing uses technical vocabulary and complex sentences, while instructive passages systematically explain concepts. Watch for the difference between presenting serious information factually versus using alarmist language to create fear.
Question 10
The notion that one must drink eight glasses of water per day is one of the most persistent myths in public health. This advice, of uncertain origin, fails to account for individual differences in body size, activity level, and climate. It also ignores the substantial amount of water we consume from food, such as fruits and vegetables, and other beverages like juice, milk, and even coffee. While staying hydrated is essential, there is no magic number. A better guideline for most healthy individuals is simply to drink when you are thirsty. The body's thirst mechanism is a finely tuned and generally reliable indicator of its need for fluids.
Which word best describes the author's tone toward the 'eight glasses a day' rule?
- Supportive
- Neutral
- Ambivalent
- Debunking (correct answer)
Explanation: When analyzing author tone on reading comprehension questions, look for specific word choices and overall attitude toward the subject matter. The author's stance becomes clear through language that either supports, criticizes, or remains neutral about a topic.
The author takes a distinctly critical stance toward the "eight glasses a day" rule. Key phrases like "persistent myths," "of uncertain origin," and "fails to account for" signal strong disagreement. The author systematically dismantles this advice by pointing out its flaws: it ignores individual differences, overlooks water from food sources, and lacks scientific basis. The definitive statement "there is no magic number" directly contradicts the rule. This pattern of identifying problems and offering contrary evidence demonstrates a debunking tone, making D correct.
Choice A (Supportive) misreads the author's position entirely—there's no endorsement of the eight-glasses rule anywhere in the passage. Choice B (Neutral) ignores the clearly critical language; a neutral tone would present both sides without taking a stance. Choice C (Ambivalent) suggests mixed feelings or uncertainty, but the author's position is consistently and firmly against the rule throughout the passage.
For HESI reading questions about author tone, focus on loaded words and phrases that reveal attitude. Words like "myth," "fails," and "ignores" are red flags indicating criticism rather than neutrality. Practice identifying whether authors are building up an idea (supportive), tearing it down (debunking), or simply presenting information without judgment (neutral).
Question 11
The integumentary system, composed of the skin, hair, and nails, serves as the body's first line of defense. The skin, the largest organ, provides a formidable physical barrier against pathogens and environmental damage. It also plays a crucial role in thermoregulation through sweat production and blood flow regulation. Furthermore, it is a major sensory organ, containing countless nerve endings that detect touch, pressure, temperature, and pain. This complex and versatile system is essential for survival, protecting internal structures while interfacing constantly with the outside world.
What is the main purpose of this passage?
- To persuade readers to take better care of their skin
- To compare the human integumentary system with that of other animals
- To provide a concise overview of the functions of the integumentary system (correct answer)
- To detail the various diseases that can affect the skin, hair, and nails
Explanation: When you encounter a reading comprehension question asking about the "main purpose" of a passage, you're being tested on your ability to identify the author's primary intent rather than getting caught up in supporting details or making assumptions beyond what's written.
This passage systematically presents the integumentary system's key functions: physical protection ("first line of defense"), thermoregulation ("sweat production and blood flow regulation"), and sensory detection ("touch, pressure, temperature, and pain"). The author provides a comprehensive but concise overview without advocating for any particular action or making comparisons. The structure moves logically from identifying the system's components to explaining its multiple roles, concluding with why it's essential for survival.
Choice A is incorrect because the passage is purely informational—there's no persuasive language or calls to action about skincare. Choice B fails because the passage focuses exclusively on humans without mentioning other animals or making any comparisons. Choice D is wrong because the passage doesn't discuss diseases at all; it only describes normal, healthy functions of the integumentary system.
Choice C correctly identifies that the passage serves as an educational overview, presenting the integumentary system's structure and functions in a clear, organized manner.
Study tip: On HESI reading questions about author's purpose, distinguish between informative passages (which teach or explain) and persuasive passages (which argue or recommend action). Look for signal words—informative passages use neutral, descriptive language, while persuasive passages include opinion words and calls to action.
Question 12
When a patient presents with symptoms of a stroke, every second counts. The medical mantra 'time is brain' reflects the reality that brain tissue rapidly begins to die when deprived of blood flow. The use of clot-busting drugs like tPA (tissue plasminogen activator) is highly effective, but only if administered within a narrow therapeutic window, typically three to four-and-a-half hours from the onset of symptoms. Public awareness campaigns that teach the F.A.S.T. acronym (Face drooping, Arm weakness, Speech difficulty, Time to call 911) are therefore not just helpful; they are a life-saving tool that empowers bystanders to act decisively.
The author's tone in this passage is best described as:
- Somber and discouraging
- Insistent and emphatic (correct answer)
- Academic and detached
- Ironic and skeptical
Explanation: When analyzing tone in reading passages, you need to identify the author's attitude and emotional approach toward the subject matter. Look for word choices, sentence structure, and the overall urgency or feeling conveyed.
This passage demonstrates an insistent and emphatic tone through several key indicators. The author uses urgent language like "every second counts" and "time is brain" to stress the critical nature of stroke treatment. The phrase "not just helpful; they are a life-saving tool" shows strong emphasis through both the semicolon structure and the escalating language from "helpful" to "life-saving." Words like "rapidly," "narrow therapeutic window," and "empowers bystanders to act decisively" all convey urgency and determination to convince readers of the importance of quick action.
Option A is incorrect because while the subject matter is serious, the author maintains an urgent, action-oriented approach rather than a discouraging one. The tone pushes for awareness and action, not despair. Option C misses the mark because the writing isn't detached—it's emotionally engaged and purposeful, using compelling language to motivate rather than simply inform. Option D is wrong because there's no irony or skepticism present; the author fully endorses the importance of rapid stroke recognition and treatment.
For HESI reading questions about tone, pay attention to emotionally charged words, sentence rhythm, and the author's apparent purpose. Authors who use urgent language, strong emphasis, and action-oriented phrases typically demonstrate an insistent, emphatic tone designed to persuade or motivate readers.
Question 13
The development of CRISPR gene-editing technology has been heralded as a monumental leap in biotechnology. Its potential applications are staggering, from correcting genetic defects that cause diseases like cystic fibrosis and sickle cell anemia to engineering more resilient crops. However, this power brings with it profound ethical questions. The possibility of creating 'designer babies' or making heritable changes to the human germline forces us to confront complex moral dilemmas about the nature of humanity and the potential for new forms of inequality. We stand at a crossroads, where the promise of healing is intertwined with the peril of hubris.
The author's tone concerning CRISPR technology can be described as:
- Uniformly celebratory
- Grave and apprehensive
- Entirely dismissive
- Awed but also concerned (correct answer)
Explanation: When you encounter tone questions on reading comprehension, you need to identify the author's overall attitude by examining both positive and negative language throughout the passage, not just isolated phrases.
The correct answer is D because the author expresses genuine admiration for CRISPR's potential while simultaneously voicing serious concerns. The passage opens by calling CRISPR a "monumental leap" with "staggering" applications for treating diseases and improving crops - this shows clear awe and respect for the technology. However, the author immediately shifts to discussing "profound ethical questions," "complex moral dilemmas," and warns about "the peril of hubris." The final metaphor of standing "at a crossroads" where "promise" is "intertwined" with "peril" perfectly captures this dual perspective of wonder mixed with worry.
Choice A is wrong because the author isn't uniformly celebratory - half the passage focuses on serious ethical concerns and potential dangers. Choice B incorrectly suggests the tone is only negative, ignoring the author's clear appreciation for CRISPR's medical and agricultural benefits. Choice C is completely off-base since the author never dismisses the technology; instead, they acknowledge its revolutionary potential while raising important cautions.
For HESI reading questions about tone, look for balance words like "however," "but," and "while" that signal the author is presenting multiple perspectives. Authors discussing cutting-edge scientific topics often adopt this nuanced tone - excited about possibilities but mindful of risks. Don't get trapped by passages that seem purely positive or negative at first glance.
Question 14
For many years, it was believed that the adult brain was static and incapable of generating new neurons. This dogma has been overturned by the discovery of adult neurogenesis, the process by which new neurons are created in specific regions of the brain, such as the hippocampus. Research has shown that factors like physical exercise, environmental enrichment, and learning can stimulate this process, whereas stress and aging can inhibit it. This remarkable neural plasticity suggests that the brain retains a capacity for self-repair and adaptation throughout life, opening new avenues for treating neurological disorders.
The primary purpose of this passage is to:
- Criticize the outdated beliefs of past neuroscientists
- Provide a set of instructions for how to increase neurogenesis
- Inform the reader about a key discovery in neuroscience and its implications (correct answer)
- Argue that neurogenesis can cure all neurological disorders
Explanation: When you encounter reading comprehension questions about primary purpose, focus on the passage's overall intent rather than specific details. Look for what the author is trying to accomplish with the entire text.
This passage follows a classic structure for informational writing: it presents an old belief that has been challenged, explains the new discovery that overturned it, describes the factors that influence this discovery, and discusses its broader significance. The author's main goal is to educate readers about adult neurogenesis - what it is, how it works, and why it matters for potential medical treatments.
Option C correctly captures this informational purpose. The passage introduces the key discovery (adult neurogenesis), explains the science behind it (factors that stimulate or inhibit the process), and discusses its implications (new treatment possibilities for neurological disorders).
Option A is too narrow and negative. While the passage mentions outdated beliefs, it doesn't criticize past scientists - it simply states that new evidence changed scientific understanding. Option B mischaracterizes the passage as instructional. The text mentions factors that affect neurogenesis but doesn't provide step-by-step instructions for enhancing it. Option D overstates the passage's claims. The text suggests neurogenesis "opens new avenues for treating" disorders, not that it can cure all neurological conditions.
For HESI reading questions, always distinguish between what the passage actually says versus what it implies, and avoid answers that are too extreme or narrow. The primary purpose is usually the broadest accurate statement about the author's main intent.
Question 15
The administration of intravenous (IV) fluids is a cornerstone of modern medical care, essential for rehydration, medication delivery, and nutritional support. However, it is not a benign procedure. Fluid overload, a condition where excess fluid accumulates in the body, can lead to serious complications, including pulmonary edema and heart failure, particularly in critically ill patients or those with renal impairment. Clinicians must therefore abandon a one-size-fits-all approach and meticulously tailor fluid therapy to the individual patient's needs, constantly reassessing for signs of overload. Precision, not volume, should be the guiding principle.
The author's primary purpose is to:
- Provide a step-by-step guide for inserting an IV line
- Warn clinicians about a specific risk and advocate for a careful approach (correct answer)
- Describe the chemical composition of standard intravenous fluids
- Recount the history of the development of intravenous therapy
Explanation: When you encounter reading comprehension questions asking about an author's "primary purpose," you need to identify the main intent behind the entire passage, not just individual details mentioned within it.
This passage follows a clear argumentative structure: it establishes that IV fluids are important in medical care, then pivots with "However, it is not a benign procedure" to highlight the serious risks of fluid overload. The author then advocates for abandoning standardized approaches in favor of individualized, careful monitoring. The concluding statement "Precision, not volume, should be the guiding principle" reinforces this call for a more cautious approach. This makes (B) correct—the author is specifically warning about fluid overload risks and advocating for careful, individualized treatment.
(A) is wrong because the passage contains no procedural steps or technical instructions for IV insertion. (C) is incorrect as there's no discussion of fluid chemistry or composition—the focus is entirely on administration practices and risks. (D) is wrong because the passage doesn't mention historical development or trace IV therapy's evolution over time.
Study tip for HESI reading questions: Primary purpose questions test your ability to distinguish between the author's main argument and supporting details. Look for transition words like "however," "therefore," and "must" that signal the author's key message. The primary purpose is usually found in the author's conclusion or recommendation, not in background information provided at the beginning.
Question 16
Anaphylaxis is a severe, life-threatening allergic reaction that can occur within seconds or minutes of exposure to an allergen. The reaction is systemic, affecting multiple body systems simultaneously. It is caused by the sudden release of chemical mediators from mast cells and basophils, leading to symptoms like hives, swelling (angioedema), difficulty breathing due to bronchial constriction, and a sharp drop in blood pressure. Immediate administration of epinephrine is the critical first-line treatment, as it works to reverse these effects. Without prompt medical intervention, anaphylaxis can be fatal.
The tone of this passage is best described as:
- Factual and urgent (correct answer)
- Hypothetical and speculative
- Reassuring and calm
- Emotional and anecdotal
Explanation: When analyzing tone in reading comprehension questions, you need to identify the author's attitude and approach toward the subject matter. Tone is revealed through word choice, sentence structure, and the overall feeling the passage conveys.
This passage demonstrates a factual and urgent tone. The factual element comes through the clinical, precise language: "systemic," "chemical mediators from mast cells and basophils," and "bronchial constriction." The author presents medical information objectively without personal opinions. The urgent tone emerges from phrases like "severe, life-threatening," "within seconds or minutes," "immediate administration," and "can be fatal." These words create a sense of time-sensitivity and critical importance.
Option B is incorrect because the passage presents established medical facts, not hypothetical scenarios or speculation. Words like "can occur" and "can be fatal" describe real possibilities, not theoretical ones. Option C fails because nothing in the passage offers comfort or reassurance—instead, it emphasizes the serious, potentially deadly nature of anaphylaxis. Option D is wrong because the passage maintains clinical objectivity without emotional language or personal stories (anecdotes).
For HESI reading questions about tone, focus on the author's word choices and purpose. Medical passages often combine factual presentation with varying degrees of urgency depending on the severity of the condition being described. Look for clinical terminology paired with words that convey time-sensitivity or severity to identify this factual-yet-urgent tone pattern.
Question 17
In the ongoing debate about healthcare reform, proposals for a single-payer system are often met with fierce opposition, citing concerns about long wait times, stifled innovation, and excessive government control. While these are valid areas for discussion, they often obscure the potential benefits: universal coverage, administrative simplicity, and the power to negotiate lower drug prices. A truly productive conversation would move beyond ideological talking points and engage in a data-driven analysis of the trade-offs inherent in any system, examining how different models have performed in other developed nations.
What is the author's primary purpose?
- To argue strongly in favor of implementing a single-payer system
- To condemn the healthcare models of all other developed nations
- To call for a more rational and evidence-based debate on healthcare (correct answer)
- To list the definitive reasons why a single-payer system would fail
Explanation: When you encounter reading comprehension questions about an author's purpose, look for the overall tone and main message rather than getting caught up in specific details or examples mentioned in the passage.
The author presents both sides of the healthcare debate fairly—acknowledging that opponents raise "valid areas for discussion" about single-payer systems while also noting potential benefits. The key phrase that reveals the author's true purpose comes at the end: calling for a "truly productive conversation" that moves "beyond ideological talking points" toward "data-driven analysis." This balanced approach and explicit call for evidence-based discussion points directly to answer C.
Looking at the incorrect options: Answer A is wrong because the author doesn't argue strongly for single-payer systems—they simply mention potential benefits while also acknowledging valid concerns. Answer B misses the mark entirely since the author actually suggests examining "how different models have performed in other developed nations," implying we should learn from them, not condemn them. Answer D incorrectly assumes the author wants to prove single-payer systems fail, when they're actually calling for objective analysis rather than predetermined conclusions.
The author maintains neutrality throughout, presenting arguments from both sides before advocating for a more rational, evidence-based approach to the entire debate.
HESI tip: When identifying an author's purpose, pay special attention to concluding statements and transition phrases like "truly productive" or "would move beyond"—these often signal the author's main intent, which may be different from the topics they discuss as examples.
Question 18
Telemedicine has expanded rapidly, offering virtual consultations as an alternative to in-person office visits. Proponents highlight its convenience, particularly for patients in rural areas or with mobility issues, and its potential to reduce healthcare costs. However, critics raise valid concerns about the limitations of remote diagnosis, the potential for patient data breaches, and the erosion of the traditional doctor-patient relationship that is built on physical presence and trust. While technology offers a promising tool, a careful, regulated approach is necessary to ensure that the quality of care is not compromised for the sake of convenience.
Which of the following best describes the author's tone in this passage?
- Enthusiastically supportive
- Strongly dismissive
- Balanced and cautionary (correct answer)
- Strictly neutral
Explanation: When analyzing author tone, you need to look beyond individual words to examine how the author presents different perspectives and what overall attitude emerges toward the topic.
The author demonstrates a balanced approach by presenting both sides of telemedicine equally. They acknowledge the benefits ("convenience," "reduce healthcare costs") while giving equal weight to legitimate concerns ("limitations of remote diagnosis," "patient data breaches"). The concluding statement reveals a cautionary stance: "a careful, regulated approach is necessary to ensure that the quality of care is not compromised." This shows measured support with important reservations.
Answer A is incorrect because "enthusiastically supportive" would mean the author strongly favors telemedicine without significant reservations. Instead, the author emphasizes potential risks and the need for regulation. Answer B is wrong because "strongly dismissive" would involve rejecting telemedicine's value entirely, but the author acknowledges it as "a promising tool." Answer D misses the mark because "strictly neutral" would mean presenting facts without any evaluative language or recommendations, yet the author clearly advocates for a "careful, regulated approach."
The correct answer is C because the author maintains balance by fairly presenting both benefits and drawbacks while taking a cautionary position about implementation.
For HESI reading questions about tone, look for evaluative language and how the author treats opposing viewpoints. Authors who present multiple perspectives fairly but offer measured recommendations typically demonstrate a "balanced and cautionary" tone rather than strict neutrality or strong bias.
Question 19
The global rise of antibiotic resistance represents one of the most significant threats to modern medicine. For decades, physicians have prescribed antibiotics for a wide range of bacterial infections, often with life-saving results. However, their overuse and misuse, both in human medicine and agriculture, have accelerated the natural process of bacterial evolution. Consequently, we are now facing 'superbugs'—strains of bacteria that are resistant to multiple antibiotics. If current trends continue, common infections and minor injuries could once again become fatal. Urgent, coordinated action is required from policymakers, healthcare providers, and the public to preserve the efficacy of these critical medicines.
What is the primary tone of the passage?
- Nostalgic and reflective
- Objective and academic
- Urgent and concerned (correct answer)
- Pessimistic and defeated
Explanation: When analyzing tone in reading passages, you're identifying the author's attitude and emotional stance toward the subject matter. Look for specific word choices, urgency markers, and the overall message the author wants to convey.
This passage demonstrates an urgent and concerned tone through several key indicators. The author uses alarm-raising language like "one of the most significant threats to modern medicine" and warns that "common infections and minor injuries could once again become fatal." The phrase "urgent, coordinated action is required" explicitly signals both immediacy and serious concern. The author isn't just presenting facts—they're actively advocating for immediate response to a critical problem.
Option A is incorrect because nostalgic writing would focus on fondly remembering the past, but this passage mentions past antibiotic success only to highlight current dangers. Option B fails because while the passage contains factual information, the emotional language and call-to-action clearly show the author's concerned perspective rather than neutral objectivity. Option D misses the mark because pessimistic and defeated writing would suggest hopelessness, but this author still believes action can "preserve the efficacy of these critical medicines"—showing concern but not defeat.
For HESI reading questions about tone, pay attention to action words and emotional intensity. Words like "urgent," "critical," "threats," and calls for immediate action typically signal concern rather than neutrality. The author's purpose—whether to inform, persuade, or warn—often reveals the tone. Here, the author clearly wants to motivate action, indicating genuine concern about a solvable problem.
Question 20
Mitosis is the process by which a single eukaryotic cell divides into two genetically identical daughter cells. This cellular division is fundamental for growth, repair, and asexual reproduction. The process is typically divided into four distinct phases: prophase, metaphase, anaphase, and telophase, followed by cytokinesis. During prophase, the chromatin condenses into visible chromosomes. In metaphase, these chromosomes align at the cell's equatorial plate. Anaphase involves the separation of sister chromatids, and in telophase, new nuclear envelopes form around the two sets of chromosomes.
The primary purpose of this passage is to:
- Argue for the importance of mitosis over meiosis
- Entertain the reader with a story about cell division
- Explain the stages of a fundamental biological process (correct answer)
- Persuade researchers to focus more on anaphase
Explanation: When you encounter reading comprehension questions about scientific passages, focus on identifying the author's primary intent rather than getting caught up in the specific details. Look at the overall structure and tone to determine the main purpose.
This passage systematically breaks down mitosis into its component parts, providing a clear, factual explanation of each phase. The author uses neutral, educational language to describe what happens during prophase, metaphase, anaphase, and telophase. The writing follows a logical sequence that moves from defining mitosis to explaining its importance, then walking through each stage step-by-step. This structure and tone clearly indicate the purpose is to inform and educate readers about this biological process, making C the correct answer.
Looking at the wrong choices: A is incorrect because the passage never mentions meiosis or makes any comparisons between different types of cell division. B misses the mark entirely—this is straightforward scientific exposition, not entertainment or storytelling. D suggests the author is trying to persuade researchers to focus on anaphase, but anaphase receives only one sentence and no special emphasis compared to the other phases.
On the HESI, reading comprehension questions often test whether you can distinguish between different purposes: explaining/informing, arguing/persuading, entertaining, or comparing. Train yourself to recognize the hallmarks of expository writing: neutral tone, logical organization, and educational content without bias or emotional language. These passages aim to teach, not convince or entertain.