USMLE Step 2 Quiz
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A 69-year-old man with long-standing, poorly controlled type 2 diabetes mellitus and an eGFR of 40 mL/min/1.73 m² is seen for routine follow-up. He is on an appropriate dose of an ACE inhibitor. His blood pressure is 138/84 mm Hg and his HbA1c is 8.5%. His urinalysis shows 3+ proteinuria. His physician is considering adding another agent to his regimen.
Which of the following medication classes has been shown to slow the progression of chronic kidney disease in patients with diabetes, independent of its effects on blood glucose?
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