USMLE Step 1 Quiz
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IMMUNOLOGY
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A 40-year-old woman with end-stage renal disease receives a kidney transplant. Her maintenance immunosuppression includes belatacept, a newer agent that interferes with T-cell activation. This drug is a fusion protein that binds to specific molecules on antigen-presenting cells, preventing them from interacting with T-cells.
Belatacept prevents T-cell activation by blocking which of the following crucial signaling pathways?
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