USMLE Step 1 Quiz
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RESPIRATORY SYSTEM
Question 1 of 20
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A 59-year-old man with a 40-pack-year history of smoking has had a productive cough with copious sputum for at least three months of the year for the past three consecutive years. On physical examination, he is cyanotic and appears overweight. His FEV1/FVC ratio is 0.60.
The primary pathologic change responsible for the symptoms in this patient is which of the following?
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