USMLE Step 1 Quiz
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MICROBIOLOGY
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A 45-year-old man with a history of alcohol use disorder is brought to the emergency department with fever, chills, and hypotension. Blood cultures are drawn and subsequently grow Escherichia coli. The patient's severe inflammatory response is primarily initiated by the recognition of lipopolysaccharide (LPS), a component of the bacterial outer membrane.
Which of the following host receptors is primarily responsible for recognizing LPS and initiating the innate immune response in this patient?
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