Practice Test 7 - USMLE Step 1
20 questions. Answer them in any order, then submit to see your score and every explanation.
- While NADH is primarily oxidized by the electron transport chain to generate ATP, NADPH is predominantly used for which of the following cellular processes?
- A 52-year-old woman has RUQ pain after fatty meals and mild jaundice; US shows gallstones. What is the most likely cause of the observed finding?
- The constellation of findings in this patient is best explained by a developmental failure of which embryologic structures due to a chromosomal microdeletion?
- This chromosomal translocation leads to the overexpression of a protein that directly promotes which of the following cellular processes?
- The therapeutic effect and the adverse effect of this drug are both caused by the inhibition of a process that normally serves to do which of the following?
- The myopathy and lactic acidosis associated with this patient's medication are primarily caused by the drug's inhibition of which of the following?
- Which of the following is the most appropriate recommendation for this patient?
- Based on this data, which of the following is the most accurate conclusion?
- This staining property is primarily attributed to the high concentration of which substance in the bacterium's cell envelope?
- A 29-year-old man plans travel to a chloroquine-resistant malaria region. He has glucose-6-phosphate dehydrogenase (G6PD) deficiency documented on prior testing. Which prophylactic medication is most appropriate and safe for this patient?
- The increased susceptibility of this patient's erythrocytes to oxidative damage is primarily due to a decreased ability to regenerate which of the following molecules?
- Which of the following techniques is most appropriate for assessing the abundance of the specific mRNA transcript in this experiment?
- A 50-year-old woman has mammography screening (sensitivity 90%, specificity 91%). Which of the following reflects the test's sensitivity?
- The BRAF gene is an example of a proto-oncogene that, when mutated, leads to constitutive activation of which of the following signaling pathways?
- How does the elevated angiotensin II level in this patient help preserve the glomerular filtration rate in the affected kidney?
- Which of the following structures forms these channels in the outer membrane?
- What is the positive predictive value (PPV) of this test in this population?
- Which of the following statistical methods is most appropriate for developing an equation to estimate GFR from serum creatinine?
- Which of the following is the most accurate interpretation of this finding?
- The medication recently started is most likely causing this patient's hyperkalemia by which of the following mechanisms?